Query: NC_003413:128228 Pyrococcus furiosus DSM 3638, complete genome Lineage: Pyrococcus furiosus; Pyrococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea General Information: This strain was isolated from a shallow marine solfataric (volcanic area that gives off sulfuric gases) region at Vulcano Island, Italy. This organism is a strictly anaerobic, hyperthermophilic archaeon. Growth occurs at temperatures between 67 and 103 degrees C, with optimal growth at 100 degrees C and a pH of 7.0. This organism is highly motile due to a bundle of flagella.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.