Query: NC_003364:1081846 Pyrobaculum aerophilum str. IM2, complete genome Lineage: Pyrobaculum aerophilum; Pyrobaculum; Thermoproteaceae; Thermoproteales; Crenarchaeota; Archaea General Information: This organism was isolated from a boiling marine water hole in Maronti Beach, Ischia, Italy. It grows optimally a 100ºC and pH 7.0. Growth can occur at temperatures between 74 and 104 ºC. Nitrate-reducing hyperthermophilic archeon. This organism is a facultatively anaerobic, nitrate-reducing hyperthermophilic archaeon. It is able to grow both aerobically and anaerobically by dissimilatory nitrate reduction.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.