Pre_GI: SWBIT SVG BLASTN

Query: NC_003155:6444500 Streptomyces avermitilis MA-4680, complete genome

Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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BLASTN Alignment.txt

Subject: NC_007963:1370903 Chromohalobacter salexigens DSM 3043, complete genome

Lineage: Chromohalobacter salexigens; Chromohalobacter; Halomonadaceae; Oceanospirillales; Proteobacteria; Bacteria

General Information: Chromohalobacter salexigens DSM 3043 was first isolated from a solar salt facility on Bonaire Island, Netherlands Antilles. A moderate halophile which can grow on a variety of salts. This bacterium is a moderate halophile, yet does not require high concentrations of sodium chloride. The salt requirements of this organism can be met by ions of other salts, such as potassium, rubidium, ammonium, bromide. Several plasmids have been isolated from this organism. Plasmid pMH1 contains genes for resistance to kanamycin, neomycin, and tetracycline. A smaller plasmid, pHE1, which does not code for antibiotic resistance genes, has also been isolated.