Pre_GI: SWBIT SVG BLASTN

Query: NC_003116:93576 Neisseria meningitidis Z2491, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: This is a serogroup A strain isolated in Gambia in 1983. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTN Alignment.txt

Subject: NC_008609:708886 Pelobacter propionicus DSM 2379, complete genome

Lineage: Pelobacter propionicus; Pelobacter; Pelobacteraceae; Desulfuromonadales; Proteobacteria; Bacteria

General Information: Common environmental anaerobe. The genus Pelobacter encompasses a unique group of fermentative microorganisms in the delta-proteobacteria. This species is ubiquitous in both marine and fresh water, and in anaerobic sedmiments. It is able to convert the unsaturated hydrocarbon acetylene to to acetate and ethanol via acetylaldehyde as an intermediate. These microorganisms may survive in some sediments as an Fe(III) or elemental sulfur reducer as well as growing fermentatively as an ethanol-oxidizing acetogen.