Pre_GI: SWBIT SVG BLASTN

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTN Alignment.txt

Subject: NC_015499:1062359 Thermodesulfobium narugense DSM 14796 chromosome, complete genome

Lineage: Thermodesulfobium narugense; Thermodesulfobium; Thermodesulfobiaceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Environment: Hot spring; Isolation: Narugo hot spring; Japan; Temp: Thermophile; Temp: 50C. This organism is a moderate thermophilic autotroph that was able to grow onH2/CO2 by sulfate respiration. It was isolated from a hot spring in Narugo, Japan.