Pre_GI: SWBIT SVG BLASTN

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTN Alignment.txt

Subject: NC_014217:3431878 Starkeya novella DSM 506 chromosome, complete genome

Lineage: Starkeya novella; Starkeya; Xanthobacteraceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Isolation: Soil; Temp: Mesophile; Temp: 26 - 30C; Habitat: Soil. Starkeya novella is a non-motile soil bacterium that belongs to the facultatively heterotrophic microbes. It is able to grow heterotrophically on a variety of single-carbon compounds, sugar alcohols, amino acids, carboxylic acids, and fatty acids. In addition, it is able to grow chemolithoautotrophically using a variety of inorganic and organic sulfur compounds such as thiosulfate, tetrathionate, dimethylsulfide (DMS), and dimethylsulfoxide.