Pre_GI: SWBIT SVG BLASTN

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTN Alignment.txt

Subject: NC_013849:1396051 Ferroglobus placidus DSM 10642 chromosome, complete genome

Lineage: Ferroglobus placidus; Ferroglobus; Archaeoglobaceae; Archaeoglobales; Euryarchaeota; Archaea

General Information: Isolation: Hallow submarine hydrothermal system at Vulcano, Italy; Temp: Hyperthermophile; Temp: 85C; Habitat: Fresh water, Hydrothermal vent. Iron-oxidizing hyperthermophilic archaeon. Ferroglobus placidus was isolated from a hydrothermal sediment at Vulcano, Italy. This organism is able to oxidize iron.