Pre_GI: SWBIT SVG BLASTN

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTN Alignment.txt

Subject: NC_012108:3922511 Desulfobacterium autotrophicum HRM2, complete genome

Lineage: Desulfobacterium autotrophicum; Desulfobacterium; Desulfobacteraceae; Desulfobacterales; Proteobacteria; Bacteria

General Information: It was isolated from a marine sediment in the Mediterranean sea near Venice, Italy. It is involved in the anaerobic mineralization of organic matter coming from the water column. Desulfobacterium autotrophicum is capable of growing litho-autotrophically with H2, CO2 and sulfate, but also by coupling sulfate reduction with the oxidation of fatty acids. This organism can transform tetra to dichlormethane.