Pre_GI: SWBIT SVG BLASTN

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTN Alignment.txt

Subject: NC_006055:183823 Mesoplasma florum L1, complete genome

Lineage: Mesoplasma florum; Mesoplasma; Entomoplasmataceae; Entomoplasmatales; Tenericutes; Bacteria

General Information: Isolated from the surface of the lemon tree flower. Bacterium which lacks a cell wall. This organism is a member of the Mollicutes which are bacteria that lack a cell wall and are obligately parasitic on a number of organisms including mammals, insects, and plants. Mesoplasma florum is a nonpathogenic organism and is nonmotile and is not closely related to Mycoplasma genitalium and Mycoplasma pneumoniae. Unlike other Mollicutes, this species does not require sterol to be supplied in the media for growth.