Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain (OY-M) is derived from a wild-type disease-causing strain (OY-W; onions yellow disease) which was isolated in Saga Prefecture, Japan, in 1982, and shows mild symptoms and does not cause stunting nor phloem hyperplasia (excessive increase in number of cells). Plant pathogenic bacterium. Phytoplasmas inhabit phloem (food-conducting vascular tissue) sieve elements of plants where they cause a variety of diseases. There is great interest in sequencing these organisms since they are currently unculturable and examination of the genome may lead to methods to deal with the diseases they cause including the development of antimicrobial agents. There is great interest in sequencing these organisms since they are currently unculturable and examination of the genome may lead to methods to deal with the diseases they cause including the development of antimicrobial agents.