Pre_GI: SWBIT SVG BLASTN

Query: NC_002976:2580485 Staphylococcus epidermidis RP62A, complete genome

Lineage: Staphylococcus epidermidis; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain is a strongly adherent, slime-producing, pathogenic strain isolated from a patient with intravascular catheter-associated sepsis. Common skin bacterium. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is the most prevalent and persistent Staphylococcus species on human skin. Has emerged as a common cause of nosocomial (hospital-acquired) infections, including catheter-associated infections and septicemia, particularly in immunocompromised patients. Highly resistant to many antibiotics including penicillins and cephalosporins.

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BLASTN Alignment.txt

Subject: NC_014014:153837 Mycoplasma crocodyli MP145 chromosome, complete genome

Lineage: Mycoplasma crocodyli; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: Mycoplasma crocodyli was isolated from the joint of a crocodile with exudative polyarthritis. The siblingspecies of M. crocodyli, Mycoplasma alligatoris causes acute lethalprimary infection of susceptible hosts, notably American alligators.This pathogen is studied to understand the mechanisms and evolutionaryorigins of that virulence. A genome survey indicated that M. alligatorisuses sialidase (Nanl) and hyaluronidase (NagH) to generate fuel forglycolysis from host cell glycans. M. crocodyli, which does not causedisease in American alligators, possesses NagH but not Nanl, so damageto the host's extracellular matrix alone cannot explain the particularvirulence of M. alligatoris.