Pre_GI: SWBIT SVG BLASTN

Query: NC_002946:1786000 Neisseria gonorrhoeae FA 1090, complete genome

Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: A serum-resistant streptomycin-resistant proline-requiring strain isolated from a patient with disseminated gonococcal infections. Causes gonorrhea. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.

Subject: NC_014614:2295131 Clostridium sticklandii, complete genome

Lineage: Clostridium sticklandii; Clostridium; unclassified Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: This Clostridium (HF strain, ATCC 12662) was initially found associated with Methanococcus vannieli in formate-enriched cultures. After its isolation in pure culture, it was shown that this organism is capable of fermenting amino acids. Biochemical studies have shown that C. sticklandii obtains energy for growth from oxidation-reduction reactions between specific amino acid pairs. Clostridium sticklandii is a Gram-positive bacterium with low (G +C) content that is capable of fermenting amino acids.