Pre_GI: SWBIT SVG BLASTN

Query: NC_002944:4254011 Mycobacterium avium subsp. paratuberculosis K-10, complete genome

Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a diary herd in Wisconsin, USA in the 1970's. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

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Subject: NC_018581:1180951 Gordonia sp. KTR9 chromosome, complete genome

Lineage: Gordonia; Gordonia; Gordoniaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from soil at an explosives testing facility. Can transform hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), a cyclic nitramine explosive. Many military ranges in the United States and Canada are contaminated with explosive and propellant residues. Of the nitroaromatic and nitramine explosives that exist on these sites, hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) has a low sorption capacity and can migrate through soil into surface water and groundwater.