Query: NC_002936:1395432 Dehalococcoides ethenogenes 195, complete genome

Lineage: Dehalococcoides mccartyi; Dehalococcoides; Dehalococcoidaceae; Dehalococcoidales; Chloroflexi; Bacteria

General Information: Dechlorinates tetrachloroethene. This organism was isolated from environments contaminated with organic chlorinated chemicals such as tetrachloroethene (PCE) and trichloroethane (TCE), common contaminants in the anaerobic subsurface. There are at least 15 organisms from different metabolic groups, halorespirators, acetogens, methanogens and facultative anaerobes, that are able to metabolize PCE. Some of these organisms couple dehalogenation to energy conservation and utilize PCE as the only source of energy while others dehalogenate tetrachloroethene fortuitously. This non-methanogenic, non-acetogenic culture is able to grow with hydrogen as the electron donor, indicating that hydrogen/PCE serves as an electron donor/acceptor for energy conservation and growth. This organism can only grow anaerobically in the presence of hydrogen as an electron donor and chlorinated compounds as electron acceptors. Dehalococcoides ethenogenes is typically found at sites contaminated with chlorinated solvents, and have been independently isolated in dozens of sites across the USA.

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BLASTN Alignment.txt

Subject: NC_013714:2477638 Bifidobacterium dentium Bd1, complete genome

Lineage: Bifidobacterium dentium; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Common oral and gut bacterium. Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. Bifidobacterium dentium species represents over forty strains which were isolated from human dental caries and human feces.