Pre_GI: SWBIT SVG BLASTN

Query: NC_002689:1507900 Thermoplasma volcanium GSS1, complete genome

Lineage: Thermoplasma volcanium; Thermoplasma; Thermoplasmataceae; Thermoplasmatales; Euryarchaeota; Archaea

General Information: This strain is the type strain for this species, and was isolated from a solfataric (volcanic area that gives off sulfuric gases) field. Thermophilic archaea. This organism is a thermophilic, acidophilic, archaea that was isolated from acidic hydrothermal vents on the shore of Aeolian Island of Vulcano, Italy. Growth of this facultative aerobe occurs at temperatures of 33-67°C with optimal at 60°C and pH of 1.0-4.0 (optimal 2.0).

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Subject: NC_013316:1 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.