Query: NC_002678:7004370 Mesorhizobium loti MAFF303099, complete genome Lineage: Mesorhizobium loti; Mesorhizobium; Phyllobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Plant symbiont bacterium. This organism contains a symbiosis island that is responsible for symbiotic relationships with plants (lotus) which is similar to what is observed with other Rhizobia that form similar relationships with legumes. The bacterium enters root nodules and performs nitrogen-fixation for the plant cell while being provided with a protective environment to grow in. Nitrogen fixation and root nodule formation genes are carried on a symbiosis island.
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General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.