Pre_GI: SWBIT SVG BLASTN

Query: NC_002663:1988000 Pasteurella multocida subsp. multocida str. Pm70, complete genome

Lineage: Pasteurella multocida; Pasteurella; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Pasteurella multocida subsp. multocida str. Pm70 was isolated in 1995 from a case of fowl cholera in chickens. Pathogen in humans, swine and poultry. This organism was one of the first pathogens ever sudied, and is named after Louis Pasteur, who used it in his vaccination studies in the 1880s. This organism usually resides in the mucous membranes of the intestinal, genital, and respiratory tissues and is an opportunistic pathogen that causes cholera in fowl, bovine hemorrhagic septicemia, and porcine atrophic rhinitis. Collectively these diseases cause millions of dollars in lost livestock every year. The organism can also infect humans if they are bitten by dogs and cats, which are carriers of the organism, but which are asymptomatic. This organism also expresses a hydrophilic capsule that inhibits phagocytosis and complemented-mediated attack.

Subject: NC_010468:111504 Escherichia coli ATCC 8739, complete genome

Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.