Query: NC_002655:1053082 Escherichia coli O157:H7 EDL933, complete genome Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: This strain (substrain) is considered a reference strain of O157:H7, which was first isolated during an outbreak in 1982. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora.E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.
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General Information: This is the type strain for this organism, which was isolated from a hydrothermal vent at a depth of 1300 m from the Lo'ihi Seamount southeast of Hawaii. This organism grows optimally in salt concentrations of 7.5 to 10%. Genome comparison has suggested that the bacterium has maintained its amino acid transport and degradation systems but lost sugar transport and certain sugar metabolic genes suggesting that it lives on amino acids rather than sugars. This may be in keeping with the environment this organism grows in, which is at hydrothermal deep sea vents that are characterized by collections of proteinaceous particles. This organism may colonize these particles by producing exopolysaccharides.