Query: NC_002607:1868371 Halobacterium sp. NRC-1, complete genome
Lineage: Halobacterium; Halobacterium; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea
General Information: Chemoheterotrophic obligate extreme halophilic archeon. This microbe (strain ATCC 700922) is an obligately halophilic archeon that has adapted to growth under conditions of extremely high salinity. Motility is via tufts of polar flagella and intracellular gas vesicles are used for buoyancy. This organism grow aerobically and its ease of culturing combined with the availability of established methods of genetic manipulation in the laboratory make it an ideal model organism for study of the archaea.
Subject: NC_007618:1792500 Brucella melitensis biovar Abortus 2308 chromosome I, complete
Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.