Query: NC_002570:126500 Bacillus halodurans C-125, complete genome Lineage: Bacillus halodurans; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Strain C-125 (JCM9153) was isolated in 1977 and is the most well studied alkaliphilic Bacillus organism. Alkaliphilic bacterium. This organism is similar to Bacillus subtilis but is alkaliphilic, grows poorly at neutral pH, and very well at pH >9.5. This bacterium produces a peptidoglycan that contains teichuronic peptides consisting of polyglutamic and polyglucuronic acids that counteract the halophilic environment.
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General Information: Mycoplasma crocodyli was isolated from the joint of a crocodile with exudative polyarthritis. The siblingspecies of M. crocodyli, Mycoplasma alligatoris causes acute lethalprimary infection of susceptible hosts, notably American alligators.This pathogen is studied to understand the mechanisms and evolutionaryorigins of that virulence. A genome survey indicated that M. alligatorisuses sialidase (Nanl) and hyaluronidase (NagH) to generate fuel forglycolysis from host cell glycans. M. crocodyli, which does not causedisease in American alligators, possesses NagH but not Nanl, so damageto the host's extracellular matrix alone cannot explain the particularvirulence of M. alligatoris.