Pre_GI: SWBIT SVG BLASTN

Query: NC_000964:521975 Bacillus subtilis subsp. subtilis str. 168, complete genome

Lineage: Bacillus subtilis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was derived in 1947 from an X-ray irradiated strain, Marburg. This organism was one of the first bacteria studied, and was named Vibrio subtilis in 1835 and renamed Bacillus subtilis in 1872. It is one of the most well characterized bacterial organisms, and is a model system for cell differentiation and development. This soil bacterium can divide asymmetrically, producing an endospore that is resistant to environmental factors such as heat, acid, and salt, and which can persist in the environment for long periods of time. The endospore is formed at times of nutritional stress, allowing the organism to persist in the environment until conditions become favorable. Prior to the decision to produce the spore the bacterium might become motile, through the production of flagella, and also take up DNA from the environment through the competence system.The sporulation process is complex and involves the coordinated regulation of hundreds of genes in the genome. This initial step results in the coordinated asymmetric cellular division and endospore formation through multiple stages that produces a single spore from the mother cell.

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BLASTN Alignment.txt

Subject: NC_018870:81396 Thermacetogenium phaeum DSM 12270 chromosome, complete genome

Lineage: Thermacetogenium phaeum; Thermacetogenium; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Nitrogen fixation. Thermophilic strictly anaerobic bacterium oxidizing acetate to CO2 in syntrophic association with a methanogenic partner. Capable of growing with various substrates such as alcohols and methylated nitrogen compounds, and to reduce sulfate in the presence of acetate. Isolated from sludge of an anaerobic digester run at 58 degrees C. Thermacetogenium phaeum is a strictly anaerobic, homoacetogenic bacterium. It is exceptional because it can use the homoacetogenic Wood-Ljungdahl (CO- dehydrogenase) pathway both for acetate formation and acetate oxidation. Acetate oxidation is possible only in syntrophic cooperation with a methanogenic partner which maintains a low hydrogen and/or formate concentration in the coculture. With this, the bacterium operates close to the thermodynamic equilibrium of substrate conversion, similar to other syntrophically fermenting bacteria such as Syntrophomonas wolfei the genomes of which have been sequenced as well in the recent past.