Query: NC_000963:803435 Rickettsia prowazekii str. Madrid E, complete genome Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.
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General Information: This species is a green sulfur bacterium which forms sedimentary biofilm layers. It has been shown to be associated with coral killed by Black-Band Disease (BBD) a microbial infection of larger coral species. This is a concern for reef conservationists as the larger species are responsible for coral scaffolds, and their reduction by disease would have considerable impact on the reef structure. While there is currently no cause-and-effect link between Prosthecochloris aestuarii and BBD, the species was found on coral which was killed by the disease and was not found on healthy coral or in the surrounding seawater.