Pre_GI: SWBIT SVG BLASTN

Query: NC_000918:1 Aquifex aeolicus VF5, complete genome

Lineage: Aquifex aeolicus; Aquifex; Aquificaceae; Aquificales; Aquificae; Bacteria

General Information: This hyperthermophilic organism grows optimally at 95 C on hydrogen, oxygen, carbon dioxide, and mineral salts. Many of the enzymes this organism produces are studied due to their heat stable nauture.

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Subject: NC_013316:81969 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.