Query: NC_000868:196015 Pyrococcus abyssi GE5, complete genome Lineage: Pyrococcus abyssi; Pyrococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea General Information: This organism was isolated from an active chimney in the North Fiji Basin of the Pacific Ocean at a depth of 3500 meters. This organism is an obligate anaerobic, hyperthermophilic archaeon. Growth occurs at a temperature of 67-103 degrees C with optimal growth at 103 degrees C at 200 atmospheres of pressure. Increased hydrostatic pressure has been found to extend the upper growth temperature and stimulate growth.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.