Pre_GI: OUP Neighbours

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Query: NC_018870:81396 Thermacetogenium phaeum DSM 12270 chromosome, complete genome

D: 33.0739

Host Lineage: Thermacetogenium phaeum; Thermacetogenium; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Nitrogen fixation. Thermophilic strictly anaerobic bacterium oxidizing acetate to CO2 in syntrophic association with a methanogenic partner. Capable of growing with various substrates such as alcohols and methylated nitrogen compounds, and to reduce sulfate in the presence of acetate. Isolated from sludge of an anaerobic digester run at 58 degrees C. Thermacetogenium phaeum is a strictly anaerobic, homoacetogenic bacterium. It is exceptional because it can use the homoacetogenic Wood-Ljungdahl (CO- dehydrogenase) pathway both for acetate formation and acetate oxidation. Acetate oxidation is possible only in syntrophic cooperation with a methanogenic partner which maintains a low hydrogen and/or formate concentration in the coculture. With this, the bacterium operates close to the thermodynamic equilibrium of substrate conversion, similar to other syntrophically fermenting bacteria such as Syntrophomonas wolfei the genomes of which have been sequenced as well in the recent past.

Number of Neighbours: 10




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_014624:1549312Eubacterium limosum KIST612 chromosome, complete genome75.1226 %Subject ←→ Query35.1735
NC_009483:3644677Geobacter uraniireducens Rf4 chromosome, complete genome75.9161 %Subject ←→ Query41.5718
NC_009483:1116385*Geobacter uraniireducens Rf4 chromosome, complete genome76.7433 %Subject ←→ Query37.4939
NC_015172:1161000Syntrophobotulus glycolicus DSM 8271 chromosome, complete genome77.3591 %Subject ←→ Query34.765
NC_018870:427357*Thermacetogenium phaeum DSM 12270 chromosome, complete genome80.2328 %Subject ←→ Query35.0803