Pre_GI: OUP Neighbours

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Query: NC_017265:1521276 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

D: 35.1936

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Number of Neighbours: 148

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_017168:2892000Yersinia pestis A1122 chromosome, complete genome95.3278 %Subject ←→ Query27.5961
NC_017160:2740870Yersinia pestis D182038 chromosome, complete genome94.4547 %Subject ←→ Query28.2618
NC_010634:3269010*Yersinia pseudotuberculosis PB1/+, complete genome75.6495 %Subject ←→ Query28.5333
NC_015224:279037Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,77.5643 %Subject ←→ Query28.7938
NC_009381:1655731Yersinia pestis Pestoides F chromosome, complete genome75.049 %Subject ←→ Query29.0263
NC_010468:1343228Escherichia coli ATCC 8739, complete genome75.3156 %Subject ←→ Query29.0512
NC_017265:2557476Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,75.8303 %Subject ←→ Query29.2631
NC_012912:4737703Dickeya zeae Ech1591, complete genome76.6942 %Subject ←→ Query29.5142
NC_017046:819414Salmonella enterica subsp. enterica serovar Typhimurium str. 79875.5637 %Subject ←→ Query29.5416
NC_012125:3905782Salmonella enterica subsp. enterica serovar Paratyphi C strain78.171 %Subject ←→ Query29.6328
NC_016857:819429Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/7475.7322 %Subject ←→ Query30.0128
NC_016810:819489Salmonella enterica subsp. enterica serovar Typhimurium str75.8517 %Subject ←→ Query30.0128
NC_015968:204969*Enterobacter asburiae LF7a chromosome, complete genome76.0172 %Subject ←→ Query30.2205
NC_012880:1711062*Dickeya dadantii Ech703, complete genome75.6618 %Subject ←→ Query30.2924
NC_008149:1221637Yersinia pestis Nepal516, complete genome76.0999 %Subject ←→ Query30.5812
NC_020063:2343813Enterobacteriaceae bacterium strain FGI 57, complete genome75.7904 %Subject ←→ Query30.8186
NC_017154:902739Yersinia pestis D106004 chromosome, complete genome79.8284 %Subject ←→ Query30.8256
NC_009708:1694685Yersinia pseudotuberculosis IP 31758 chromosome, complete genome94.0012 %Subject ←→ Query30.9126
NC_012880:1127997*Dickeya dadantii Ech703, complete genome77.7359 %Subject ←→ Query30.9614
NC_020181:1057476Enterobacter aerogenes EA1509E, complete genome75.4289 %Subject ←→ Query31.0919
NC_006155:3040769Yersinia pseudotuberculosis IP 32953, complete genome95.0797 %Subject ←→ Query31.1041
NC_006511:3759550Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC77.9197 %Subject ←→ Query31.1345
NC_010634:2960000Yersinia pseudotuberculosis PB1/+, complete genome94.0717 %Subject ←→ Query31.2014
NC_012962:3864000*Photorhabdus asymbiotica, complete genome75.7537 %Subject ←→ Query31.492
NC_014029:961522Yersinia pestis Z176003 chromosome, complete genome79.7763 %Subject ←→ Query31.5068
NC_017168:3948514Yersinia pestis A1122 chromosome, complete genome75.818 %Subject ←→ Query31.5192
NC_011149:3895921Salmonella enterica subsp. enterica serovar Agona str. SL483,77.5521 %Subject ←→ Query31.5601
NC_004088:1801819Yersinia pestis KIM, complete genome93.5355 %Subject ←→ Query31.8002
NC_004631:3841975Salmonella enterica subsp. enterica serovar Typhi Ty2, complete77.7512 %Subject ←→ Query32.0647
NC_010102:3919999Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,77.3652 %Subject ←→ Query32.0708
NC_003197:3971905Salmonella typhimurium LT2, complete genome77.4908 %Subject ←→ Query32.0829
NC_008149:2411161Yersinia pestis Nepal516, complete genome97.8186 %Subject ←→ Query32.2349
NC_014029:1512605Yersinia pestis Z176003 chromosome, complete genome77.6409 %Subject ←→ Query32.2364
NC_012125:793812*Salmonella enterica subsp. enterica serovar Paratyphi C strain75.7506 %Subject ←→ Query32.2957
NC_020064:1547524Serratia marcescens FGI94, complete genome75.6434 %Subject ←→ Query32.3124
NC_011083:3985618Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,77.4816 %Subject ←→ Query32.4599
NC_003198:3855157Salmonella enterica subsp. enterica serovar Typhi str. CT18,77.8064 %Subject ←→ Query32.5632
NC_010465:1724000Yersinia pseudotuberculosis YPIII, complete genome95.8762 %Subject ←→ Query32.6727
NC_013592:3397304Dickeya dadantii Ech586, complete genome76.8505 %Subject ←→ Query32.6808
NC_010634:1565788Yersinia pseudotuberculosis PB1/+, complete genome78.2567 %Subject ←→ Query33.0113
NC_017160:905783Yersinia pestis D182038 chromosome, complete genome78.6795 %Subject ←→ Query33.1867
NC_006155:1567306Yersinia pseudotuberculosis IP 32953, complete genome78.2782 %Subject ←→ Query33.2342
NC_012880:3645304Dickeya dadantii Ech703, complete genome75.4902 %Subject ←→ Query33.3293
NC_017168:4363000Yersinia pestis A1122 chromosome, complete genome78.6795 %Subject ←→ Query33.4186
NC_017154:3139614Yersinia pestis D106004 chromosome, complete genome95.3217 %Subject ←→ Query33.4691
NC_009381:588137Yersinia pestis Pestoides F chromosome, complete genome79.2065 %Subject ←→ Query33.692
NC_008800:1497746Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,85.6311 %Subject ←→ Query33.823
NC_003143:2849377Yersinia pestis CO92, complete genome98.3395 %Subject ←→ Query33.8521
NC_010159:1861465Yersinia pestis Angola, complete genome98.2874 %Subject ←→ Query33.8947
NC_005810:2613456Yersinia pestis biovar Microtus str. 91001, complete genome98.3885 %Subject ←→ Query33.9433
NC_015224:3191000Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,84.5435 %Subject ←→ Query34.0665
NC_013592:3618248*Dickeya dadantii Ech586, complete genome78.076 %Subject ←→ Query34.4581
NC_011415:11381*Escherichia coli SE11 chromosome, complete genome77.0558 %Subject ←→ Query34.6212
NC_011741:11381*Escherichia coli IAI1 chromosome, complete genome76.8474 %Subject ←→ Query34.732
NC_016514:2647984*Enterobacter cloacae EcWSU1 chromosome, complete genome77.7727 %Subject ←→ Query35.4683
NC_013421:1545386Pectobacterium wasabiae WPP163, complete genome77.1752 %Subject ←→ Query35.9253
NC_013421:1143500Pectobacterium wasabiae WPP163, complete genome76.9884 %Subject ←→ Query36.4256
NC_012962:3568046Photorhabdus asymbiotica, complete genome77.5888 %Subject ←→ Query37.813
NC_011149:2040396Salmonella enterica subsp. enterica serovar Agona str. SL483,77.0098 %Subject ←→ Query37.9381
NC_005126:1265071Photorhabdus luminescens subsp. laumondii TTO1, complete genome75.2053 %Subject ←→ Query37.9976
NC_013892:853366Xenorhabdus bovienii SS-2004 chromosome, complete genome78.5325 %Subject ←→ Query38.0885
NC_016863:3933848Salmonella enterica subsp. enterica serovar Typhimurium str. UK-177.7053 %Subject ←→ Query39.056
NC_011147:3755725Salmonella enterica subsp. enterica serovar Paratyphi A str77.9565 %Subject ←→ Query39.0564
NC_017046:3991551Salmonella enterica subsp. enterica serovar Typhimurium str. 79877.4326 %Subject ←→ Query39.0657
NC_016810:3993863Salmonella enterica subsp. enterica serovar Typhimurium str77.6746 %Subject ←→ Query39.1598
NC_016857:3993864Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/7477.6654 %Subject ←→ Query39.189
NC_016856:3985597Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S77.4969 %Subject ←→ Query39.3604
NC_011080:3941909Salmonella enterica subsp. enterica serovar Newport str. SL254,77.693 %Subject ←→ Query39.4334
NC_012962:1661683Photorhabdus asymbiotica, complete genome78.8971 %Subject ←→ Query40.4188
NC_011094:3853036Salmonella enterica subsp. enterica serovar Schwarzengrund str77.3713 %Subject ←→ Query40.4943
NC_016818:2542295*Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, complete75.7169 %Subject ←→ Query40.8603
NC_014228:3282500Xenorhabdus nematophila ATCC 19061, complete genome75.1011 %Subject ←→ Query41.4806
NC_020064:3998715*Serratia marcescens FGI94, complete genome78.0545 %Subject Query49.6448
NC_014541:1165991Ferrimonas balearica DSM 9799 chromosome, complete genome76.011 %Subject Query51.4043