Pre_GI: OUP Neighbours

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Query: NC_015571:722815 Porphyromonas gingivalis TDC60, complete genome

D: 31.2952

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

Number of Neighbours: 16

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_010729:1385217Porphyromonas gingivalis ATCC 33277, complete genome80.6127 %Subject ←→ Query26.4044
NC_010729:1344903*Porphyromonas gingivalis ATCC 33277, complete genome81.6513 %Subject ←→ Query28.6722
NC_010729:1462135Porphyromonas gingivalis ATCC 33277, complete genome75.8609 %Subject ←→ Query29.2315
NC_002950:2098454Porphyromonas gingivalis W83, complete genome79.5588 %Subject ←→ Query29.9884
NC_015571:260664*Porphyromonas gingivalis TDC60, complete genome75.9896 %Subject ←→ Query30.2975
NC_010729:2147268*Porphyromonas gingivalis ATCC 33277, complete genome76.7586 %Subject ←→ Query31.9808
NC_015571:290355*Porphyromonas gingivalis TDC60, complete genome77.8646 %Subject ←→ Query32.3231
NC_002950:1981155Porphyromonas gingivalis W83, complete genome81.6422 %Subject ←→ Query32.6605
NC_015571:1207000Porphyromonas gingivalis TDC60, complete genome80.5913 %Subject ←→ Query33.9518
NC_015571:1030527Porphyromonas gingivalis TDC60, complete genome75.3707 %Subject ←→ Query34.085
NC_002950:1270132Porphyromonas gingivalis W83, complete genome80.2604 %Subject ←→ Query34.3389
NC_015571:168617*Porphyromonas gingivalis TDC60, complete genome79.9602 %Subject ←→ Query35.8726
NC_002950:1334500*Porphyromonas gingivalis W83, complete genome75.4871 %Subject ←→ Query36.3983
NC_015571:1265121*Porphyromonas gingivalis TDC60, complete genome75.4044 %Subject ←→ Query37.7493
NC_015311:1860666Prevotella denticola F0289 chromosome, complete genome75.6311 %Subject ←→ Query41.2926
NC_014364:3001597Spirochaeta smaragdinae DSM 11293 chromosome, complete genome76.6299 %Subject Query43.5079