Pre_GI: OUP Neighbours

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Query: NC_015571:411156 Porphyromonas gingivalis TDC60, complete genome

D: 32.6171

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

Number of Neighbours: 25

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_008508:1382036Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1,76.296 %Subject Query17.8569
NC_008510:1339926Leptospira borgpetersenii serovar Hardjo-bovis JB197 chromosome 1,76.2408 %Subject Query17.8979
NC_014774:671695Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, complete75.723 %Subject Query20.4767
NC_002620:229856Chlamydia muridarum Nigg, complete genome75.0306 %Subject ←→ Query22.9754
NC_015152:272500Spirochaeta sp. Buddy chromosome, complete genome75.0582 %Subject ←→ Query28.3895
NC_015160:1117371Odoribacter splanchnicus DSM 20712 chromosome, complete genome75.0337 %Subject ←→ Query28.7816
NC_010729:1014957Porphyromonas gingivalis ATCC 33277, complete genome75.8548 %Subject ←→ Query30.0401
NC_002950:209569Porphyromonas gingivalis W83, complete genome79.2555 %Subject ←→ Query30.2934
NC_015571:1065775Porphyromonas gingivalis TDC60, complete genome80.432 %Subject ←→ Query30.9847
NC_015571:2002489*Porphyromonas gingivalis TDC60, complete genome76.4308 %Subject ←→ Query31.3475
NC_006347:5027580Bacteroides fragilis YCH46, complete genome77.0374 %Subject ←→ Query32.0586
NC_015152:2549756*Spirochaeta sp. Buddy chromosome, complete genome75.481 %Subject ←→ Query32.9075
NC_002950:1511955*Porphyromonas gingivalis W83, complete genome75.2451 %Subject ←→ Query33.0544
NC_006347:2154906Bacteroides fragilis YCH46, complete genome75.1593 %Subject ←→ Query33.3688
NC_002950:1571383Porphyromonas gingivalis W83, complete genome75.9007 %Subject ←→ Query33.7002
NC_014364:4578408Spirochaeta smaragdinae DSM 11293 chromosome, complete genome77.9749 %Subject ←→ Query34.4426
NC_002950:879930*Porphyromonas gingivalis W83, complete genome77.6869 %Subject ←→ Query34.5736
NC_010729:1179008*Porphyromonas gingivalis ATCC 33277, complete genome78.0362 %Subject ←→ Query34.8701
NC_012491:743883*Brevibacillus brevis NBRC 100599, complete genome75.7169 %Subject ←→ Query35.5725
NC_011830:4722607Desulfitobacterium hafniense DCB-2, complete genome75.3615 %Subject ←→ Query35.7585
NC_014364:667841Spirochaeta smaragdinae DSM 11293 chromosome, complete genome77.6685 %Subject ←→ Query36.4759
NC_015164:1952500Bacteroides salanitronis DSM 18170 chromosome, complete genome75.8058 %Subject ←→ Query37.3063
NC_014364:2246524*Spirochaeta smaragdinae DSM 11293 chromosome, complete genome76.3664 %Subject ←→ Query37.5351
NC_014364:2322269*Spirochaeta smaragdinae DSM 11293 chromosome, complete genome76.3174 %Subject ←→ Query39.7692
NC_014364:394899Spirochaeta smaragdinae DSM 11293 chromosome, complete genome78.943 %Subject Query44.1589