Pre_GI: OUP Neighbours

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Query: NC_015571:168617 Porphyromonas gingivalis TDC60, complete genome

D: 35.8726

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

Number of Neighbours: 20




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_010729:1385217Porphyromonas gingivalis ATCC 33277, complete genome75.242 %Subject ←→ Query26.4044
NC_010729:1344903*Porphyromonas gingivalis ATCC 33277, complete genome77.6654 %Subject ←→ Query28.6722
NC_014507:611625*Methanoplanus petrolearius DSM 11571 chromosome, complete genome75.0613 %Subject ←→ Query29.1121
NC_010729:1462135Porphyromonas gingivalis ATCC 33277, complete genome76.2929 %Subject ←→ Query29.2315
NC_002950:2098454Porphyromonas gingivalis W83, complete genome80.6832 %Subject ←→ Query29.9884
NC_010729:2038118Porphyromonas gingivalis ATCC 33277, complete genome83.9032 %Subject ←→ Query30.0584
NC_015571:722815*Porphyromonas gingivalis TDC60, complete genome79.9602 %Subject ←→ Query31.2952
NC_015571:290355*Porphyromonas gingivalis TDC60, complete genome79.1115 %Subject ←→ Query32.3231
NC_002950:1981155Porphyromonas gingivalis W83, complete genome83.4957 %Subject ←→ Query32.6605
NC_015571:801715Porphyromonas gingivalis TDC60, complete genome77.5551 %Subject ←→ Query33.0257
NC_015571:1207000Porphyromonas gingivalis TDC60, complete genome79.5037 %Subject ←→ Query33.9518
NC_002950:1270132Porphyromonas gingivalis W83, complete genome78.75 %Subject ←→ Query34.3389
NC_014364:2751662*Spirochaeta smaragdinae DSM 11293 chromosome, complete genome76.6238 %Subject ←→ Query36.1819
NC_015160:231276Odoribacter splanchnicus DSM 20712 chromosome, complete genome76.3235 %Subject ←→ Query36.7168
NC_014364:2717865Spirochaeta smaragdinae DSM 11293 chromosome, complete genome76.9822 %Subject ←→ Query38.439
NC_014935:1389000Nitratifractor saLSUginis DSM 16511 chromosome, complete genome76.4124 %Subject ←→ Query38.7212
NC_014364:4488875Spirochaeta smaragdinae DSM 11293 chromosome, complete genome77.1569 %Subject ←→ Query40.795
NC_014364:3001597Spirochaeta smaragdinae DSM 11293 chromosome, complete genome75.5239 %Subject ←→ Query43.5079
NC_015690:3941113*Paenibacillus mucilaginosus KNP414 chromosome, complete genome75.098 %Subject ←→ Query44.4181
NC_014935:1704816Nitratifractor saLSUginis DSM 16511 chromosome, complete genome75.818 %Subject Query52.884