Pre_GI: OUP Neighbours

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Query: NC_015571:1030527 Porphyromonas gingivalis TDC60, complete genome

D: 34.085

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

Number of Neighbours: 15

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_010729:1344903*Porphyromonas gingivalis ATCC 33277, complete genome75.0551 %Subject ←→ Query28.6722
NC_015571:260664*Porphyromonas gingivalis TDC60, complete genome77.9044 %Subject ←→ Query30.2975
NC_015571:722815*Porphyromonas gingivalis TDC60, complete genome75.3707 %Subject ←→ Query31.2952
NC_014371:889043Prevotella melaninogenica ATCC 25845 chromosome chromosome II,77.6287 %Subject ←→ Query31.4256
NC_002950:2068500*Porphyromonas gingivalis W83, complete genome77.3897 %Subject ←→ Query31.7607
NC_010729:2147268*Porphyromonas gingivalis ATCC 33277, complete genome78.9675 %Subject ←→ Query31.9808
NC_015436:202384Spirochaeta coccoides DSM 17374 chromosome, complete genome76.5472 %Subject ←→ Query32.4295
NC_002950:1981155Porphyromonas gingivalis W83, complete genome75.1256 %Subject ←→ Query32.6605
NC_010729:225616*Porphyromonas gingivalis ATCC 33277, complete genome76.9669 %Subject ←→ Query33.4401
NC_015571:1207000Porphyromonas gingivalis TDC60, complete genome77.6899 %Subject ←→ Query33.9518
NC_002950:1270132Porphyromonas gingivalis W83, complete genome78.7071 %Subject ←→ Query34.3389
NC_014370:885937Prevotella melaninogenica ATCC 25845 chromosome chromosome I,77.6654 %Subject ←→ Query34.8736
NC_015311:1827000Prevotella denticola F0289 chromosome, complete genome77.8094 %Subject ←→ Query40.9724
NC_015311:1860666Prevotella denticola F0289 chromosome, complete genome81.394 %Subject ←→ Query41.2926
NC_014364:3001597Spirochaeta smaragdinae DSM 11293 chromosome, complete genome75.4626 %Subject ←→ Query43.5079