Pre_GI: OUP MCL Sub Cluster Neighbours

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Query: NC_015571:168617 Porphyromonas gingivalis TDC60, complete genome

D: 35.8726

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host DescriptionProposed Island FlowSubject Island D
NC_010729:1385217Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query26.4044
NC_016633:14000*Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomeSubject ←→ Query28.052
NC_015436:1*Spirochaeta coccoides DSM 17374 chromosome, complete genomeSubject ←→ Query28.2253
NC_015436:440033*Spirochaeta coccoides DSM 17374 chromosome, complete genomeSubject ←→ Query28.6539
NC_010729:1344903*Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query28.6722
NC_015436:1287873Spirochaeta coccoides DSM 17374 chromosome, complete genomeSubject ←→ Query28.6965
NC_015152:2528399*Spirochaeta sp. Buddy chromosome, complete genomeSubject ←→ Query28.7391
NC_015436:1322087Spirochaeta coccoides DSM 17374 chromosome, complete genomeSubject ←→ Query28.7731
NC_010729:1462135Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query29.2315
NC_002950:2098454Porphyromonas gingivalis W83, complete genomeSubject ←→ Query29.9884
NC_010729:2038118Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query30.0584
NC_015571:260664*Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query30.2975
NC_015152:2622000Spirochaeta sp. Buddy chromosome, complete genomeSubject ←→ Query30.8925
NC_020210:3341976Geobacillus sp. GHH01, complete genomeSubject ←→ Query30.9309
NC_015571:722815*Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query31.2952
NC_014371:889043Prevotella melaninogenica ATCC 25845 chromosome chromosome II,Subject ←→ Query31.4256
NC_002950:2068500*Porphyromonas gingivalis W83, complete genomeSubject ←→ Query31.7607
NC_016610:2605922Tannerella forsythia ATCC 43037 chromosome, complete genomeSubject ←→ Query31.9553
NC_010729:2147268*Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query31.9808
NC_015571:290355*Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query32.3231
NC_015152:2887414Spirochaeta sp. Buddy chromosome, complete genomeSubject ←→ Query32.3869
NC_015436:202384Spirochaeta coccoides DSM 17374 chromosome, complete genomeSubject ←→ Query32.4295
NC_015571:2273503*Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query32.6012
NC_002950:1981155Porphyromonas gingivalis W83, complete genomeSubject ←→ Query32.6605
NC_009615:3993187*Parabacteroides distasonis ATCC 8503 chromosome, complete genomeSubject ←→ Query32.9645
NC_015571:801715Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query33.0257
NC_016610:2077603*Tannerella forsythia ATCC 43037 chromosome, complete genomeSubject ←→ Query33.0638
NC_014371:177536*Prevotella melaninogenica ATCC 25845 chromosome chromosome II,Subject ←→ Query33.1534
NC_009615:1553556Parabacteroides distasonis ATCC 8503 chromosome, complete genomeSubject ←→ Query33.1753
NC_010729:225616*Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query33.4401
NC_009328:3322802Geobacillus thermodenitrificans NG80-2 chromosome, complete genomeSubject ←→ Query33.7828
NC_015571:1207000Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query33.9518
NC_015571:1030527Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query34.085
NC_020409:192508*Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeSubject ←→ Query34.1172
NC_002950:1270132Porphyromonas gingivalis W83, complete genomeSubject ←→ Query34.3389
NC_014364:1990000Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query34.5057
NC_020409:1589044Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeSubject ←→ Query34.5797
NC_015152:2026049Spirochaeta sp. Buddy chromosome, complete genomeSubject ←→ Query34.834
NC_014370:885937Prevotella melaninogenica ATCC 25845 chromosome chromosome I,Subject ←→ Query34.8736
NC_014364:2562281*Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query35.4937
NC_016610:795903Tannerella forsythia ATCC 43037 chromosome, complete genomeSubject ←→ Query35.7081
NC_015571:168617*Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query35.8726
NC_014364:2693840Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query35.977
NC_002950:115917*Porphyromonas gingivalis W83, complete genomeSubject ←→ Query36.0378
NC_015152:2831566Spirochaeta sp. Buddy chromosome, complete genomeSubject ←→ Query36.129
NC_014364:1116439Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query36.1585
NC_014364:2751662*Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query36.1819
NC_009614:4201098Bacteroides vulgatus ATCC 8482 chromosome, complete genomeSubject ←→ Query36.3604
NC_002950:1334500*Porphyromonas gingivalis W83, complete genomeSubject ←→ Query36.3983
NC_015160:231276Odoribacter splanchnicus DSM 20712 chromosome, complete genomeSubject ←→ Query36.7168
NC_010729:1549744*Porphyromonas gingivalis ATCC 33277, complete genomeSubject ←→ Query37.1352
NC_016776:215500Bacteroides fragilis 638R, complete genomeSubject ←→ Query37.6263
NC_015571:1265121*Porphyromonas gingivalis TDC60, complete genomeSubject ←→ Query37.7493
NC_016077:998741*Acidaminococcus intestini RyC-MR95 chromosome, complete genomeSubject ←→ Query37.9222
NC_009483:4434375*Geobacter uraniireducens Rf4 chromosome, complete genomeSubject ←→ Query37.9438
NC_014364:894373*Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query38.0711
NC_014935:1389000Nitratifractor saLSUginis DSM 16511 chromosome, complete genomeSubject ←→ Query38.7212
NC_014364:4488875Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query40.795
NC_015311:1860666Prevotella denticola F0289 chromosome, complete genomeSubject ←→ Query41.2926
NC_014364:3001597Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeSubject ←→ Query43.5079
NC_015501:1941851*Porphyromonas asaccharolytica DSM 20707 chromosome, completeSubject Query49.4604
NC_019968:1147409*Prevotella dentalis DSM 3688 chromosome 2, complete sequenceSubject Query51.4094
NC_015501:1762450Porphyromonas asaccharolytica DSM 20707 chromosome, completeSubject Query52.7445
NC_019968:382991*Prevotella dentalis DSM 3688 chromosome 2, complete sequenceSubject Query53.2135
NC_019968:1235500Prevotella dentalis DSM 3688 chromosome 2, complete sequenceSubject Query54.3913
NC_019968:1084288*Prevotella dentalis DSM 3688 chromosome 2, complete sequenceSubject Query56.3063
NC_019968:1304450*Prevotella dentalis DSM 3688 chromosome 2, complete sequenceSubject Query58.5325
NC_019968:1194489*Prevotella dentalis DSM 3688 chromosome 2, complete sequenceSubject Query59.0569