Pre_GI: OUP Neighbours

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Query: NC_011333:1040192 Helicobacter pylori G27 chromosome, complete genome

D: 23.376

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Helicobacter pylori is a gram-negative pathogen that colonizes the stomachs of over half the world's population. Originally isolated from an endoscopy patient from Grosseto Hospital (Tuscany, Italy). Causes peptic ulcers. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.

Number of Neighbours: 139




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_020411:90538*Hydrogenobaculum sp. HO, complete genome77.4479 %Subject ←→ Query16.2117
NC_020411:278000*Hydrogenobaculum sp. HO, complete genome75.1961 %Subject ←→ Query16.7406
NC_020411:114683*Hydrogenobaculum sp. HO, complete genome76.4124 %Subject ←→ Query16.7578
NC_017297:2796000Clostridium botulinum F str. 230613 chromosome, complete genome75.1103 %Subject ←→ Query17.0021
NC_020411:1333352*Hydrogenobaculum sp. HO, complete genome76.3848 %Subject ←→ Query17.0385
NC_012622:1579927*Sulfolobus islandicus Y.G.57.14 chromosome, complete genome75.098 %Subject ←→ Query17.1085
NC_020411:583503*Hydrogenobaculum sp. HO, complete genome79.2739 %Subject ←→ Query17.133
NC_020411:905335*Hydrogenobaculum sp. HO, complete genome76.8719 %Subject ←→ Query17.3273
NC_012588:211633Sulfolobus islandicus M.14.25 chromosome, complete genome76.6085 %Subject ←→ Query17.3577
NC_012726:2461102Sulfolobus islandicus M.16.4 chromosome, complete genome75.4289 %Subject ←→ Query18.0507
NC_012726:287637Sulfolobus islandicus M.16.4 chromosome, complete genome76.2347 %Subject ←→ Query18.0873
NC_012622:1395601*Sulfolobus islandicus Y.G.57.14 chromosome, complete genome76.8444 %Subject ←→ Query18.446
NC_012726:255774Sulfolobus islandicus M.16.4 chromosome, complete genome76.0876 %Subject ←→ Query18.4521
NC_017276:2080102Sulfolobus islandicus REY15A chromosome, complete genome75.2819 %Subject ←→ Query18.4825
NC_012623:2774910Sulfolobus islandicus Y.N.15.51 chromosome, complete genome76.2561 %Subject ←→ Query18.514
NC_012622:1010210Sulfolobus islandicus Y.G.57.14 chromosome, complete genome75.6771 %Subject ←→ Query18.8256
NC_012623:929080*Sulfolobus islandicus Y.N.15.51 chromosome, complete genome75.2849 %Subject ←→ Query18.9196
NC_012632:243982Sulfolobus islandicus M.16.27 chromosome, complete genome75.9773 %Subject ←→ Query19.0145
NC_012632:2654200Sulfolobus islandicus M.16.27 chromosome, complete genome76.2592 %Subject ←→ Query19.0304
NC_012973:49208Helicobacter pylori B38 chromosome, complete genome82.2549 %Subject ←→ Query19.054
NC_017366:1055319*Helicobacter pylori F32, complete genome86.0815 %Subject ←→ Query19.3397
NC_020411:981888*Hydrogenobaculum sp. HO, complete genome75.7384 %Subject ←→ Query19.3397
NC_012726:2549813Sulfolobus islandicus M.16.4 chromosome, complete genome76.4308 %Subject ←→ Query19.6996
NC_017275:927814*Sulfolobus islandicus HVE10/4 chromosome, complete genome75.7169 %Subject ←→ Query19.7089
NC_012622:2662428Sulfolobus islandicus Y.G.57.14 chromosome, complete genome75.5729 %Subject ←→ Query19.7288
NC_012622:2376405Sulfolobus islandicus Y.G.57.14 chromosome, complete genome75.1195 %Subject ←→ Query19.741
NC_012632:2415739*Sulfolobus islandicus M.16.27 chromosome, complete genome75.7567 %Subject ←→ Query19.7672
NC_011498:1571840Helicobacter pylori P12, complete genome83.4773 %Subject ←→ Query19.8717
NC_012632:2564801Sulfolobus islandicus M.16.27 chromosome, complete genome75.046 %Subject ←→ Query19.8991
NC_018939:1583653Helicobacter pylori 26695 chromosome, complete genome82.4295 %Subject ←→ Query19.949
NC_020125:1545578Riemerella anatipestifer RA-CH-2, complete genome76.3511 %Subject ←→ Query20.0024
NC_013769:2335062Sulfolobus islandicus L.D.8.5 chromosome, complete genome75.7384 %Subject ←→ Query20.0136
NC_012973:967380Helicobacter pylori B38 chromosome, complete genome85.9773 %Subject ←→ Query20.0403
NC_017276:2240069*Sulfolobus islandicus REY15A chromosome, complete genome75.6495 %Subject ←→ Query20.0778
NC_013769:2685000Sulfolobus islandicus L.D.8.5 chromosome, complete genome76.0509 %Subject ←→ Query20.1869
NC_014555:47372Helicobacter pylori PeCan4 chromosome, complete genome81.7463 %Subject ←→ Query20.197
NC_000915:53715Helicobacter pylori 26695, complete genome84.4301 %Subject ←→ Query20.2152
NC_018939:53715Helicobacter pylori 26695 chromosome, complete genome84.3964 %Subject ←→ Query20.2152
NC_017276:2481083Sulfolobus islandicus REY15A chromosome, complete genome75.1195 %Subject ←→ Query20.2173
NC_017367:1505780*Helicobacter pylori F57, complete genome83.8603 %Subject ←→ Query20.2456
NC_017362:992293Helicobacter pylori Lithuania75 chromosome, complete genome84.3015 %Subject ←→ Query20.2912
NC_017378:986611Helicobacter pylori Puno120 chromosome, complete genome83.1556 %Subject ←→ Query20.3429
NC_018939:454000Helicobacter pylori 26695 chromosome, complete genome90.8732 %Subject ←→ Query20.4645
NC_017355:997089Helicobacter pylori v225d chromosome, complete genome85.4902 %Subject ←→ Query20.4784
NC_017275:2615814Sulfolobus islandicus HVE10/4 chromosome, complete genome76.011 %Subject ←→ Query20.5534
NC_017275:2327479Sulfolobus islandicus HVE10/4 chromosome, complete genome75.723 %Subject ←→ Query20.5663
NC_014555:1477934*Helicobacter pylori PeCan4 chromosome, complete genome82.5092 %Subject ←→ Query20.7685
NC_020125:170245Riemerella anatipestifer RA-CH-2, complete genome75.8027 %Subject ←→ Query20.8262
NC_017359:813500Helicobacter pylori Sat464 chromosome, complete genome88.413 %Subject ←→ Query20.9371
NC_017375:1317398*Helicobacter pylori 83 chromosome, complete genome78.318 %Subject ←→ Query21.0664
NC_014738:167707Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,76.9424 %Subject ←→ Query21.0977
NC_017354:1465925*Helicobacter pylori 52 chromosome, complete genome83.2904 %Subject ←→ Query21.1302
NC_017365:1466500*Helicobacter pylori F30, complete genome84.8805 %Subject ←→ Query21.1355
NC_017045:328031Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,76.9424 %Subject ←→ Query21.2032
NC_017378:1489818*Helicobacter pylori Puno120 chromosome, complete genome84.3352 %Subject ←→ Query21.2062
NC_017361:930280*Helicobacter pylori SouthAfrica7 chromosome, complete genome96.1765 %Subject ←→ Query21.4337
NC_017360:1052473*Helicobacter pylori 35A chromosome, complete genome89.2524 %Subject ←→ Query21.4344
NC_017372:902043*Helicobacter pylori India7 chromosome, complete genome82.9902 %Subject ←→ Query21.4433
NC_017378:1518529Helicobacter pylori Puno120 chromosome, complete genome88.7469 %Subject ←→ Query21.4852
NC_017371:1030148Helicobacter pylori Gambia94/24 chromosome, complete genome93.5233 %Subject ←→ Query21.5743
NC_017367:278916Helicobacter pylori F57, complete genome95.6097 %Subject ←→ Query21.7822
NC_014555:1526775Helicobacter pylori PeCan4 chromosome, complete genome95.0735 %Subject ←→ Query21.8455
NC_017362:1512959Helicobacter pylori Lithuania75 chromosome, complete genome89.9847 %Subject ←→ Query21.8502
NC_014560:53750Helicobacter pylori SJM180 chromosome, complete genome83.5478 %Subject ←→ Query21.9905
NC_014256:448710Helicobacter pylori B8 chromosome, complete genome93.0178 %Subject ←→ Query22.0728
NC_017368:852490*Helicobacter pylori F16, complete genome88.5294 %Subject ←→ Query22.1065
NC_017381:982216Helicobacter pylori 2018 chromosome, complete genome91.3143 %Subject ←→ Query22.1098
NC_017357:973392Helicobacter pylori 908 chromosome, complete genome91.492 %Subject ←→ Query22.1512
NC_018939:1044000Helicobacter pylori 26695 chromosome, complete genome91.5411 %Subject ←→ Query22.1555
NC_014560:171931*Helicobacter pylori SJM180 chromosome, complete genome83.6305 %Subject ←→ Query22.2094
NC_017365:848500*Helicobacter pylori F30, complete genome88.5478 %Subject ←→ Query22.2678
NC_017376:538000Helicobacter pylori SNT49 chromosome, complete genome87.6348 %Subject ←→ Query22.3371
NC_017374:974279Helicobacter pylori 2017 chromosome, complete genome91.4951 %Subject ←→ Query22.3751
NC_017355:1299874*Helicobacter pylori v225d chromosome, complete genome78.8205 %Subject ←→ Query22.3918
NC_014256:683384*Helicobacter pylori B8 chromosome, complete genome88.1219 %Subject ←→ Query22.4101
NC_014560:1366747Helicobacter pylori SJM180 chromosome, complete genome92.5827 %Subject ←→ Query22.4172
NC_017361:1303553*Helicobacter pylori SouthAfrica7 chromosome, complete genome78.6581 %Subject ←→ Query22.4343
NC_017355:493237*Helicobacter pylori v225d chromosome, complete genome85.9712 %Subject ←→ Query22.497
NC_011333:1236730*Helicobacter pylori G27 chromosome, complete genome80.4013 %Subject ←→ Query22.505
NC_017063:834674Helicobacter pylori ELS37 chromosome, complete genome90.0766 %Subject ←→ Query22.5255
NC_017063:775337*Helicobacter pylori ELS37 chromosome, complete genome84.8713 %Subject ←→ Query22.6411
NC_017376:57500Helicobacter pylori SNT49 chromosome, complete genome95.6618 %Subject ←→ Query22.6458
NC_017354:848500*Helicobacter pylori 52 chromosome, complete genome88.0515 %Subject ←→ Query22.7001
NC_017367:562918Helicobacter pylori F57, complete genome88.367 %Subject ←→ Query22.7778
NC_018939:547793Helicobacter pylori 26695 chromosome, complete genome85.7629 %Subject ←→ Query22.8113
NC_017361:1528239Helicobacter pylori SouthAfrica7 chromosome, complete genome94.1575 %Subject ←→ Query22.851
NC_017375:872478*Helicobacter pylori 83 chromosome, complete genome88.5233 %Subject ←→ Query22.9485
NC_017379:996500Helicobacter pylori Puno135 chromosome, complete genome88.2537 %Subject ←→ Query23.0394
NC_017358:220900Helicobacter pylori Cuz20 chromosome, complete genome96.5257 %Subject ←→ Query23.078
NC_014560:1309470*Helicobacter pylori SJM180 chromosome, complete genome80.0582 %Subject ←→ Query23.0849
NC_017378:502806Helicobacter pylori Puno120 chromosome, complete genome86.9087 %Subject ←→ Query23.0891
NC_017371:530673Helicobacter pylori Gambia94/24 chromosome, complete genome86.2439 %Subject ←→ Query23.1308
NC_017379:1233482*Helicobacter pylori Puno135 chromosome, complete genome81.5411 %Subject ←→ Query23.2065
NC_011333:514464Helicobacter pylori G27 chromosome, complete genome87.3284 %Subject ←→ Query23.2936
NC_014560:518582*Helicobacter pylori SJM180 chromosome, complete genome87.2089 %Subject ←→ Query23.2968
NC_011498:1345623*Helicobacter pylori P12, complete genome78.2751 %Subject ←→ Query23.322
NC_017357:495213Helicobacter pylori 908 chromosome, complete genome90.0429 %Subject ←→ Query23.3524
NC_017371:1470582*Helicobacter pylori Gambia94/24 chromosome, complete genome89.7028 %Subject ←→ Query23.3827
NC_017358:563336Helicobacter pylori Cuz20 chromosome, complete genome88.3241 %Subject ←→ Query23.4728
NC_017379:505350Helicobacter pylori Puno135 chromosome, complete genome88.1863 %Subject ←→ Query23.5439
NC_017358:1342000*Helicobacter pylori Cuz20 chromosome, complete genome78.5386 %Subject ←→ Query23.5469
NC_014256:636000*Helicobacter pylori B8 chromosome, complete genome84.8284 %Subject ←→ Query23.553
NC_017371:1601452*Helicobacter pylori Gambia94/24 chromosome, complete genome82.7972 %Subject ←→ Query23.6245
NC_014256:485969Helicobacter pylori B8 chromosome, complete genome89.954 %Subject ←→ Query23.6492
NC_017379:1035464Helicobacter pylori Puno135 chromosome, complete genome93.2996 %Subject ←→ Query23.6756
NC_017375:77142Helicobacter pylori 83 chromosome, complete genome88.3854 %Subject ←→ Query23.6929
NC_000921:1343701*Helicobacter pylori J99, complete genome77.4663 %Subject ←→ Query23.6929
NC_017366:535188Helicobacter pylori F32, complete genome85.9651 %Subject ←→ Query23.9333
NC_017358:182854*Helicobacter pylori Cuz20 chromosome, complete genome76.1336 %Subject ←→ Query24.0093
NC_017063:800156Helicobacter pylori ELS37 chromosome, complete genome87.1354 %Subject ←→ Query24.0797
NC_017374:498588Helicobacter pylori 2017 chromosome, complete genome87.6072 %Subject ←→ Query24.1336
NC_017381:500699Helicobacter pylori 2018 chromosome, complete genome87.5521 %Subject ←→ Query24.1686
NC_017372:855384*Helicobacter pylori India7 chromosome, complete genome88.6274 %Subject ←→ Query24.1732
NC_017362:506950Helicobacter pylori Lithuania75 chromosome, complete genome86.7647 %Subject ←→ Query24.4401
NC_017372:748097Helicobacter pylori India7 chromosome, complete genome87.9902 %Subject ←→ Query24.6808
NC_017371:1358000*Helicobacter pylori Gambia94/24 chromosome, complete genome78.0699 %Subject ←→ Query24.6899
NC_017365:77150*Helicobacter pylori F30, complete genome78.9246 %Subject ←→ Query24.696
NC_017063:1362000*Helicobacter pylori ELS37 chromosome, complete genome78.4773 %Subject ←→ Query24.921
NC_014555:502151Helicobacter pylori PeCan4 chromosome, complete genome87.0558 %Subject ←→ Query24.9588
NC_017378:1175639*Helicobacter pylori Puno120 chromosome, complete genome82.9871 %Subject ←→ Query24.9757
NC_017376:1324000*Helicobacter pylori SNT49 chromosome, complete genome77.5245 %Subject ←→ Query25.0669
NC_017372:1373766*Helicobacter pylori India7 chromosome, complete genome78.2567 %Subject ←→ Query25.1034
NC_017372:1212000*Helicobacter pylori India7 chromosome, complete genome75.3891 %Subject ←→ Query25.3379
NC_000921:1147394Helicobacter pylori J99, complete genome81.2408 %Subject ←→ Query25.3465
NC_017368:1300000*Helicobacter pylori F16, complete genome79.5098 %Subject ←→ Query25.7174
NC_017375:1498000Helicobacter pylori 83 chromosome, complete genome89.5312 %Subject ←→ Query26.3679
NC_008229:118000*Helicobacter acinonychis str. Sheeba, complete genome79.3015 %Subject ←→ Query26.5139
NC_020411:765500*Hydrogenobaculum sp. HO, complete genome77.9902 %Subject ←→ Query26.5463
NC_017367:1333811*Helicobacter pylori F57, complete genome79.0839 %Subject ←→ Query26.6233
NC_015557:1232772*Hydrogenobaculum sp. 3684 chromosome, complete genome75.2972 %Subject ←→ Query27.1019
NC_015587:1232642*Hydrogenobaculum sp. SHO chromosome, complete genome75.2941 %Subject ←→ Query27.19
NC_017368:468934Helicobacter pylori F16, complete genome77.6593 %Subject ←→ Query28.2271
NC_020411:1232962*Hydrogenobaculum sp. HO, complete genome75.1991 %Subject ←→ Query28.5177
NC_011126:1241655*Hydrogenobaculum sp. Y04AAS1, complete genome75.6587 %Subject ←→ Query29.5923
NC_014810:9081Helicobacter felis ATCC 49179, complete genome80.8456 %Subject ←→ Query30.1131
NC_015674:1114915Helicobacter bizzozeronii CIII-1, complete genome77.0925 %Subject ←→ Query30.3076
NC_015674:66000Helicobacter bizzozeronii CIII-1, complete genome80.0643 %Subject ←→ Query31.475
NC_015674:1605923Helicobacter bizzozeronii CIII-1, complete genome83.2292 %Subject ←→ Query31.6766
NC_015674:1562968*Helicobacter bizzozeronii CIII-1, complete genome81.6605 %Subject Query37.5085