Pre_GI: OUP Neighbours

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Query: NC_010287:957862 Chlamydia trachomatis 434/Bu, complete genome

D: 23.6199

Host Lineage: Chlamydia trachomatis; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This is a biovar, serovar L2 strain. Serovar L2 strains are associated with sexually transmitted infections. L2 strains cause lymphogranuloma vernerum, a systemic infection which infects monocytes and spreads to lymph nodes causing swelling. Causes disease in either the eye or the urogenital tract. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Chlamydia trachomatis causes infection that leads to blindness and sexually transmitted diseases in humans. There are 15 serovariants that preferentially cause disease in either the eye or the urogenital tract. The trachoma (infection of the mucous membrane of the eyelids) biovars are noninvasive and can cause blinding trachoma (variants A, B, Ba, and C), or sexually transmitted diseases (variants, D, E, F, G, H, I, J, and K). The lymphogranuloma venereum biovars (variants L1, L2, and L3) can cross the epithelial cells of mucous membranes and then travel through the lymphatic system where they multiply within mononuclear phagocytes found within the lymph nodes.

Number of Neighbours: 9




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_010280:957890*Chlamydia trachomatis L2b/UCH-1/proctitis, complete genome99.7396 %Subject ←→ Query24.1792
NC_000117:639268*Chlamydia trachomatis D/UW-3/CX, complete genome95.9344 %Subject ←→ Query24.2461
NC_015470:1096232*Chlamydophila psittaci 6BC chromosome, complete genome83.7531 %Subject ←→ Query21.9084
NC_015408:561987Chlamydophila pecorum E58 chromosome, complete genome81.5748 %Subject ←→ Query26.3011
NC_007429:49647Chlamydia trachomatis A/HAR-13, complete genome81.4614 %Subject ←→ Query25.608
NC_015744:900000*Chlamydia trachomatis L2c chromosome, complete genome80.8517 %Subject ←→ Query27.6386
NC_007429:585774*Chlamydia trachomatis A/HAR-13, complete genome80.6985 %Subject ←→ Query24.5136
NC_013009:225722*Neorickettsia risticii str. Illinois, complete genome77.7482 %Subject ←→ Query30.3647
NC_015713:1927297Simkania negevensis Z chromosome gsn.131, complete genome76.0907 %Subject ←→ Query26.006