Pre_GI: OUP Neighbours

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Query: NC_010161:2548254 Bartonella tribocorum CIP 105476, complete genome

D: 31.3939

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.

Number of Neighbours: 24

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_005955:1259393*Bartonella quintana str. Toulouse, complete genome77.3039 %Subject ←→ Query23.094
NC_005956:1139342*Bartonella henselae str. Houston-1, complete genome76.1703 %Subject ←→ Query23.553
NC_000921:1343701*Helicobacter pylori J99, complete genome75.0797 %Subject ←→ Query23.6929
NC_013512:126915*Sulfurospirillum deleyianum DSM 6946, complete genome78.3609 %Subject ←→ Query25.149
NC_002942:1109618Legionella pneumophila subsp. pneumophila str. Philadelphia 1,75.7935 %Subject ←→ Query25.2542
NC_008783:145305Bartonella bacilliformis KC583, complete genome85.6464 %Subject ←→ Query26.0032
NC_008229:118000*Helicobacter acinonychis str. Sheeba, complete genome75.3493 %Subject ←→ Query26.5139
NC_005955:1284500*Bartonella quintana str. Toulouse, complete genome77.8309 %Subject ←→ Query27.0975
NC_012982:2415237Hirschia baltica ATCC 49814, complete genome77.7849 %Subject ←→ Query27.8696
NC_010161:1811000*Bartonella tribocorum CIP 105476, complete genome77.5337 %Subject ←→ Query27.9374
NC_012846:2004711*Bartonella grahamii as4aup, complete genome80.2819 %Subject ←→ Query27.95
NC_013721:1581370*Gardnerella vaginalis 409-05, complete genome75.0643 %Subject ←→ Query29.3242
NC_010161:1598000*Bartonella tribocorum CIP 105476, complete genome77.2886 %Subject ←→ Query30.262
NC_009654:4624459Marinomonas sp. MWYL1, complete genome75.8088 %Subject ←→ Query30.4991
NC_015559:3511231Marinomonas posidonica IVIA-Po-181 chromosome, complete genome75.867 %Subject ←→ Query30.6283
NC_008783:177161*Bartonella bacilliformis KC583, complete genome80.2482 %Subject ←→ Query30.6709
NC_010161:1949637Bartonella tribocorum CIP 105476, complete genome91.4645 %Subject ←→ Query31.1808
NC_005956:1648000*Bartonella henselae str. Houston-1, complete genome77.6348 %Subject ←→ Query31.2454
NC_010161:1324381Bartonella tribocorum CIP 105476, complete genome88.0024 %Subject ←→ Query31.3762
NC_015559:1478114Marinomonas posidonica IVIA-Po-181 chromosome, complete genome75.1899 %Subject ←→ Query32.0839
NC_010161:2155500*Bartonella tribocorum CIP 105476, complete genome80.1103 %Subject ←→ Query32.5841
NC_009654:4716417Marinomonas sp. MWYL1, complete genome77.5245 %Subject ←→ Query32.6103
NC_015581:1043394Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome75.5208 %Subject ←→ Query32.6716
NC_002506:207097*Vibrio cholerae O1 biovar eltor str. N16961 chromosome II, complete75.9681 %Subject ←→ Query37.898