Pre_GI: OUP Neighbours

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Query: NC_008767:1739344 Neisseria meningitidis FAM18, complete genome

D: 33.4813

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Number of Neighbours: 13

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_002946:684728Neisseria gonorrhoeae FA 1090, complete genome75.6924 %Subject ←→ Query30.2475
NC_003116:1734000Neisseria meningitidis Z2491, complete genome81.9516 %Subject ←→ Query30.3786
NC_010120:1313500Neisseria meningitidis 053442, complete genome75.3585 %Subject ←→ Query31.5054
NC_010120:144000*Neisseria meningitidis 053442, complete genome82.6593 %Subject ←→ Query32.4921
NC_003112:1594000Neisseria meningitidis MC58, complete genome78.0974 %Subject ←→ Query32.6666
NC_010120:609323*Neisseria meningitidis 053442, complete genome75.8241 %Subject ←→ Query33.1254
NC_008767:613394*Neisseria meningitidis FAM18, complete genome75.8977 %Subject ←→ Query34.1821
NC_008767:1829500*Neisseria meningitidis FAM18, complete genome78.3425 %Subject ←→ Query34.2169
NC_008767:1321129*Neisseria meningitidis FAM18, complete genome77.7574 %Subject ←→ Query34.4104
NC_014752:1063506Neisseria lactamica ST-640, complete genome77.2978 %Subject ←→ Query35.8436
NC_003116:291661*Neisseria meningitidis Z2491, complete genome76.5656 %Subject ←→ Query39.4107
NC_014752:197000*Neisseria lactamica ST-640, complete genome76.4185 %Subject ←→ Query40.1397
NC_003112:2215184*Neisseria meningitidis MC58, complete genome77.0466 %Subject ←→ Query40.7794