Pre_GI: OUP Neighbours

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Query: NC_005956:1648000 Bartonella henselae str. Houston-1, complete genome

D: 31.2454

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.

Number of Neighbours: 21

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Select all Donors or Recipients for Query Island

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_005955:1259393*Bartonella quintana str. Toulouse, complete genome77.9228 %Subject ←→ Query23.094
NC_005956:1139342*Bartonella henselae str. Houston-1, complete genome76.8321 %Subject ←→ Query23.553
NC_005956:1521736Bartonella henselae str. Houston-1, complete genome76.152 %Subject ←→ Query24.4934
NC_007429:585774*Chlamydia trachomatis A/HAR-13, complete genome78.848 %Subject ←→ Query24.5136
NC_013512:126915*Sulfurospirillum deleyianum DSM 6946, complete genome76.2714 %Subject ←→ Query25.149
NC_008783:145305Bartonella bacilliformis KC583, complete genome78.8388 %Subject ←→ Query26.0032
NC_015408:561987Chlamydophila pecorum E58 chromosome, complete genome77.5429 %Subject ←→ Query26.3011
NC_005955:1284500*Bartonella quintana str. Toulouse, complete genome80.4351 %Subject ←→ Query27.0975
NC_015744:900000*Chlamydia trachomatis L2c chromosome, complete genome78.5355 %Subject ←→ Query27.6386
NC_010161:1811000*Bartonella tribocorum CIP 105476, complete genome80.7935 %Subject ←→ Query27.9374
NC_012846:2004711*Bartonella grahamii as4aup, complete genome86.2561 %Subject ←→ Query27.95
NC_015276:2804874*Marinomonas mediterranea MMB-1 chromosome, complete genome76.9608 %Subject ←→ Query29.8547
NC_010161:1598000*Bartonella tribocorum CIP 105476, complete genome77.6562 %Subject ←→ Query30.262
NC_013009:225722*Neorickettsia risticii str. Illinois, complete genome80.0766 %Subject ←→ Query30.3647
NC_015276:2852010Marinomonas mediterranea MMB-1 chromosome, complete genome75.1226 %Subject ←→ Query30.4475
NC_008783:177161*Bartonella bacilliformis KC583, complete genome78.845 %Subject ←→ Query30.6709
NC_010161:1949637Bartonella tribocorum CIP 105476, complete genome76.1887 %Subject ←→ Query31.1808
NC_010161:2548254Bartonella tribocorum CIP 105476, complete genome77.6348 %Subject ←→ Query31.3939
NC_006138:1245944*Desulfotalea psychrophila LSv54, complete genome75.5729 %Subject ←→ Query32.3163
NC_010161:2155500*Bartonella tribocorum CIP 105476, complete genome86.0907 %Subject ←→ Query32.5841
NC_015276:2171355*Marinomonas mediterranea MMB-1 chromosome, complete genome76.0172 %Subject ←→ Query32.7927