Pre_GI: OUP Neighbours

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Query: NC_005810:4469156 Yersinia pestis biovar Microtus str. 91001, complete genome

D: 29.5112

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Number of Neighbours: 86

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_004088:266543Yersinia pestis KIM, complete genome94.5895 %Subject ←→ Query30.0081
NC_008149:4053363Yersinia pestis Nepal516, complete genome94.4455 %Subject ←→ Query30.0006
NC_010465:429095Yersinia pseudotuberculosis YPIII, complete genome84.807 %Subject ←→ Query29.1646
NC_003143:4006884Yersinia pestis CO92, complete genome83.5294 %Subject ←→ Query29.6176
NC_006155:4302826Yersinia pseudotuberculosis IP 32953, complete genome83.0392 %Subject ←→ Query30.1556
NC_010634:4234932Yersinia pseudotuberculosis PB1/+, complete genome82.9289 %Subject ←→ Query30.3016
NC_012779:3316877Edwardsiella ictaluri 93-146, complete genome81.2531 %Subject ←→ Query34.9445
NC_014228:3282500Xenorhabdus nematophila ATCC 19061, complete genome81.1091 %Subject Query41.4806
NC_013961:3083816Erwinia amylovora, complete genome79.8254 %Subject ←→ Query36.2172
NC_012779:3176820*Edwardsiella ictaluri 93-146, complete genome79.3566 %Subject Query39.7546
NC_009648:2465613*Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome79.0074 %Subject Query50.7802
NC_006155:1567306Yersinia pseudotuberculosis IP 32953, complete genome78.7684 %Subject ←→ Query33.2342
NC_012779:2064582Edwardsiella ictaluri 93-146, complete genome78.7623 %Subject ←→ Query37.0151
NC_012779:2424967*Edwardsiella ictaluri 93-146, complete genome78.6458 %Subject ←→ Query35.992
NC_008149:1221637Yersinia pestis Nepal516, complete genome78.462 %Subject ←→ Query30.5812
NC_010634:1565788Yersinia pseudotuberculosis PB1/+, complete genome78.4069 %Subject ←→ Query33.0113
NC_012779:1449500*Edwardsiella ictaluri 93-146, complete genome78.0392 %Subject Query41.6091
NC_003143:2778494Yersinia pestis CO92, complete genome77.8615 %Subject ←→ Query30.2293
NC_007712:1893066*Sodalis glossinidius str. 'morsitans', complete genome77.7788 %Subject ←→ Query32.276
NC_012779:2928000*Edwardsiella ictaluri 93-146, complete genome77.4816 %Subject Query41.5453
NC_007712:2287053Sodalis glossinidius str. 'morsitans', complete genome77.4786 %Subject ←→ Query36.533
NC_013592:1424560Dickeya dadantii Ech586, complete genome77.4112 %Subject Query41.2418
NC_010067:3753971Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete77.3529 %Subject ←→ Query35.7065
NC_008150:3529430Yersinia pestis Antiqua, complete genome77.1814 %Subject ←→ Query31.4433
NC_004088:3955933Yersinia pestis KIM, complete genome77.1415 %Subject ←→ Query33.4603
NC_010159:1101241Yersinia pestis Angola, complete genome77.1078 %Subject ←→ Query33.9894
NC_003143:645559Yersinia pestis CO92, complete genome77.1078 %Subject ←→ Query34.4007
NC_005810:3238391Yersinia pestis biovar Microtus str. 91001, complete genome77.0741 %Subject ←→ Query34.2139
NC_012962:3568046Photorhabdus asymbiotica, complete genome77.0588 %Subject ←→ Query37.813
NC_009648:1487692Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome76.9884 %Subject Query49.6231
NC_010694:3055403Erwinia tasmaniensis, complete genome76.9669 %Subject ←→ Query35.0644
NC_007712:433500Sodalis glossinidius str. 'morsitans', complete genome76.8627 %Subject ←→ Query37.0845
NC_009778:3832000Enterobacter sakazakii ATCC BAA-894, complete genome76.8444 %Subject Query45.4902
NC_009648:3476000Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome76.7739 %Subject ←→ Query37.4593
NC_012779:305969Edwardsiella ictaluri 93-146, complete genome76.7524 %Subject Query39.836
NC_008563:3119284Escherichia coli APEC O1, complete genome76.7341 %Subject ←→ Query31.9127
NC_003198:3824187Salmonella enterica subsp. enterica serovar Typhi str. CT18,76.6973 %Subject ←→ Query35.4207
NC_010634:4045794Yersinia pseudotuberculosis PB1/+, complete genome76.6942 %Subject ←→ Query34.0011
NC_006905:3942753Salmonella enterica subsp. enterica serovar Choleraesuis str76.682 %Subject ←→ Query35.749
NC_006155:4105542Yersinia pseudotuberculosis IP 32953, complete genome76.6789 %Subject ←→ Query34.268
NC_004631:3809678Salmonella enterica subsp. enterica serovar Typhi Ty2, complete76.6054 %Subject ←→ Query36.1376
NC_009832:1946401Serratia proteamaculans 568, complete genome76.5809 %Subject ←→ Query35.908
NC_012779:996879Edwardsiella ictaluri 93-146, complete genome76.5778 %Subject Query39.7678
NC_010067:632683Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete76.5472 %Subject ←→ Query35.8098
AP010958:1472506Escherichia coli O103:H2 str. 12009 DNA, complete genome76.4583 %Subject ←→ Query36.7127
NC_014228:2883500Xenorhabdus nematophila ATCC 19061, complete genome76.4216 %Subject ←→ Query39.0811
NC_014500:3519722Dickeya dadantii 3937 chromosome, complete genome76.394 %Subject ←→ Query32.164
NC_014500:894136Dickeya dadantii 3937 chromosome, complete genome76.2194 %Subject ←→ Query37.8586
NC_011080:2342672Salmonella enterica subsp. enterica serovar Newport str. SL254,76.1366 %Subject ←→ Query37.4165
NC_012912:325913Dickeya zeae Ech1591, complete genome76.0968 %Subject ←→ Query32.3565
NC_011149:2040396Salmonella enterica subsp. enterica serovar Agona str. SL483,76.0907 %Subject ←→ Query37.9381
NC_015566:4662171Serratia sp. AS12 chromosome, complete genome76.0754 %Subject Query41.8855
NC_013508:2356865*Edwardsiella tarda EIB202, complete genome75.9436 %Subject Query44.5077
CU928160:256932Escherichia coli IAI1 chromosome, complete genome75.9314 %Subject ←→ Query34.5956
NC_013716:4824541*Citrobacter rodentium ICC168, complete genome75.9069 %Subject ←→ Query38.2235
NC_013421:1954915*Pectobacterium wasabiae WPP163, complete genome75.9038 %Subject ←→ Query32.6483
NC_014121:1038554Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete75.8395 %Subject ←→ Query34.8127
NC_003198:2297837Salmonella enterica subsp. enterica serovar Typhi str. CT18,75.8303 %Subject ←→ Query37.159
NC_007712:4023516Sodalis glossinidius str. 'morsitans', complete genome75.7996 %Subject ←→ Query33.8969
NC_006905:2355290Salmonella enterica subsp. enterica serovar Choleraesuis str75.7874 %Subject ←→ Query37.6094
NC_012779:2856051Edwardsiella ictaluri 93-146, complete genome75.7598 %Subject Query40.677
NC_005126:1265071Photorhabdus luminescens subsp. laumondii TTO1, complete genome75.7292 %Subject ←→ Query37.9976
NC_013283:113660Cronobacter turicensis plasmid pCTU1, complete sequence75.72 %Subject Query42.151
NC_006511:682863*Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC75.6985 %Subject ←→ Query36.3874
NC_004631:685357*Salmonella enterica subsp. enterica serovar Typhi Ty2, complete75.6373 %Subject ←→ Query36.1113
NC_009648:293052*Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome75.6036 %Subject Query43.5401
NC_013508:876431*Edwardsiella tarda EIB202, complete genome75.5024 %Subject Query41.7282
NC_011149:2294500Salmonella enterica subsp. enterica serovar Agona str. SL483,75.4504 %Subject ←→ Query38.0253
NC_002655:1909139Escherichia coli O157:H7 EDL933, complete genome75.4228 %Subject ←→ Query38.4667
NC_013282:3719500*Cronobacter turicensis, complete genome75.383 %Subject ←→ Query31.6817
NC_004431:1352906Escherichia coli CFT073, complete genome75.3431 %Subject ←→ Query36.4239
NC_014228:3022903Xenorhabdus nematophila ATCC 19061, complete genome75.3309 %Subject ←→ Query39.1304
NC_009792:808332Citrobacter koseri ATCC BAA-895, complete genome75.3309 %Subject ←→ Query35.0274
NC_012779:2281700*Edwardsiella ictaluri 93-146, complete genome75.2911 %Subject Query40.1776
NC_010067:171053Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete75.2757 %Subject ←→ Query31.5722
NC_013282:1256769Cronobacter turicensis, complete genome75.2757 %Subject ←→ Query38.8742
NC_011080:3976441Salmonella enterica subsp. enterica serovar Newport str. SL254,75.2635 %Subject ←→ Query36.5166
NC_008253:2198583Escherichia coli 536, complete genome75.2267 %Subject ←→ Query30.9551
NC_011149:3930358Salmonella enterica subsp. enterica serovar Agona str. SL483,75.2206 %Subject ←→ Query38.0507
NC_011750:919953Escherichia coli IAI39 chromosome, complete genome75.2083 %Subject ←→ Query38.6045
NC_012912:1229333Dickeya zeae Ech1591, complete genome75.1899 %Subject ←→ Query32.2592
NC_010102:3955479Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,75.1685 %Subject ←→ Query37.2943
NC_003197:4005857Salmonella typhimurium LT2, complete genome75.1103 %Subject ←→ Query36.3904
NC_013592:2160000Dickeya dadantii Ech586, complete genome75.1103 %Subject ←→ Query33.4874
NC_010694:614985Erwinia tasmaniensis, complete genome75.0827 %Subject ←→ Query35.5876
NC_012779:957558Edwardsiella ictaluri 93-146, complete genome75.0705 %Subject ←→ Query38.2879