Pre_GI: OUP Neighbours

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Query: NC_005810:3493607 Yersinia pestis biovar Microtus str. 91001, complete genome

D: 37.8405

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Number of Neighbours: 73




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
AC_000091:1083798*Escherichia coli W3110 DNA, complete genome75.6464 %Subject Query27.055
NC_008258:2190635*Shigella flexneri 5 str. 8401, complete genome75.5699 %Subject ←→ Query28.1068
NC_004088:1265730Yersinia pestis KIM, complete genome76.9148 %Subject ←→ Query28.3925
NC_010498:1094000Escherichia coli SMS-3-5, complete genome75.3339 %Subject ←→ Query28.4077
NC_000913:1087062*Escherichia coli K12, complete genome76.7555 %Subject ←→ Query28.4107
NC_008149:1195614Yersinia pestis Nepal516, complete genome76.8137 %Subject ←→ Query28.4229
NC_008150:4561633*Yersinia pestis Antiqua, complete genome75.7751 %Subject ←→ Query28.4594
NC_007613:3470314Shigella boydii Sb227, complete genome75.5545 %Subject ←→ Query28.5683
NC_009800:2083465*Escherichia coli HS, complete genome75.5944 %Subject ←→ Query28.6965
NC_010465:3958766Yersinia pseudotuberculosis YPIII, complete genome75.4013 %Subject ←→ Query28.7816
NC_005810:515744*Yersinia pestis biovar Microtus str. 91001, complete genome75.4902 %Subject ←→ Query28.8059
NC_004088:1622941Yersinia pestis KIM, complete genome76.826 %Subject ←→ Query29.0444
NC_004088:4116676Yersinia pestis KIM, complete genome75.6219 %Subject ←→ Query29.2173
NC_006155:3237990Yersinia pseudotuberculosis IP 32953, complete genome75.6281 %Subject ←→ Query29.2589
NC_003143:483395*Yersinia pestis CO92, complete genome75.7935 %Subject ←→ Query29.2984
NC_010498:4967724*Escherichia coli SMS-3-5, complete genome75.8487 %Subject ←→ Query29.3045
NC_010473:3722571Escherichia coli str. K-12 substr. DH10B, complete genome75.7874 %Subject ←→ Query29.369
NC_010465:893921Yersinia pseudotuberculosis YPIII, complete genome76.8719 %Subject ←→ Query29.369
NC_010159:409500*Yersinia pestis Angola, complete genome77.7022 %Subject ←→ Query29.3874
NC_010465:1550617Yersinia pseudotuberculosis YPIII, complete genome76.7831 %Subject ←→ Query29.4243
NC_004088:1909880*Yersinia pestis KIM, complete genome76.3297 %Subject ←→ Query29.6267
NC_006155:456000*Yersinia pseudotuberculosis IP 32953, complete genome76.1121 %Subject ←→ Query29.6905
NC_010159:3779129Yersinia pestis Angola, complete genome75.6219 %Subject ←→ Query29.8673
NC_008149:402599*Yersinia pestis Nepal516, complete genome76.6942 %Subject ←→ Query30.0082
NC_010634:2004653Yersinia pseudotuberculosis PB1/+, complete genome76.0662 %Subject ←→ Query30.0158
NC_004741:2169877*Shigella flexneri 2a str. 2457T, complete genome75.0153 %Subject ←→ Query30.0188
NC_003143:1691000Yersinia pestis CO92, complete genome75.8609 %Subject ←→ Query30.0863
NC_006155:713174*Yersinia pseudotuberculosis IP 32953, complete genome75.2849 %Subject ←→ Query30.0948
NC_005810:1230976Yersinia pestis biovar Microtus str. 91001, complete genome76.5686 %Subject ←→ Query30.2833
NC_015224:1914833*Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,75.7169 %Subject ←→ Query30.3745
CP002185:3822470Escherichia coli W, complete genome75.4228 %Subject ←→ Query30.5172
NC_006155:2084669*Yersinia pseudotuberculosis IP 32953, complete genome76.8781 %Subject ←→ Query30.5265
NC_010159:809663Yersinia pestis Angola, complete genome75.4534 %Subject ←→ Query30.5995
NC_010634:4150763Yersinia pseudotuberculosis PB1/+, complete genome77.3713 %Subject ←→ Query30.8229
NC_006155:1807902Yersinia pseudotuberculosis IP 32953, complete genome75.4626 %Subject ←→ Query30.987
NC_005810:2739878Yersinia pestis biovar Microtus str. 91001, complete genome76.8168 %Subject ←→ Query31.0068
NC_010468:1816359*Escherichia coli ATCC 8739, complete genome76.348 %Subject ←→ Query31.2101
NC_008149:1317109Yersinia pestis Nepal516, complete genome76.8382 %Subject ←→ Query31.2606
NC_008150:4140804Yersinia pestis Antiqua, complete genome76.777 %Subject ←→ Query31.3862
NC_004088:2937077Yersinia pestis KIM, complete genome79.2463 %Subject ←→ Query31.4263
NC_003143:3115933Yersinia pestis CO92, complete genome75.6005 %Subject ←→ Query31.481
NC_008149:2773139Yersinia pestis Nepal516, complete genome76.9516 %Subject ←→ Query31.5189
NC_008150:2822689Yersinia pestis Antiqua, complete genome76.3634 %Subject ←→ Query31.5428
NC_011740:1189455*Escherichia fergusonii ATCC 35469, complete genome75.8517 %Subject ←→ Query31.5591
NC_008150:2681327Yersinia pestis Antiqua, complete genome76.8382 %Subject ←→ Query31.5965
NC_014228:4360676*Xenorhabdus nematophila ATCC 19061, complete genome79.375 %Subject ←→ Query31.6041
NC_006155:4210606Yersinia pseudotuberculosis IP 32953, complete genome77.3652 %Subject ←→ Query31.6963
CP002516:4199133Escherichia coli KO11, complete genome75.3248 %Subject ←→ Query31.8604
NC_010634:4001154Yersinia pseudotuberculosis PB1/+, complete genome75.242 %Subject ←→ Query31.9978
NC_010465:2582080*Yersinia pseudotuberculosis YPIII, complete genome76.6238 %Subject ←→ Query32.0464
NC_003143:3346834Yersinia pestis CO92, complete genome75.4657 %Subject ←→ Query32.1752
NC_003143:4105754Yersinia pestis CO92, complete genome77.402 %Subject ←→ Query32.2349
NC_010159:2878499Yersinia pestis Angola, complete genome75.1593 %Subject ←→ Query32.4356
NC_010634:3129174Yersinia pseudotuberculosis PB1/+, complete genome75.3064 %Subject ←→ Query32.6052
NC_005810:2549680Yersinia pestis biovar Microtus str. 91001, complete genome75.4779 %Subject ←→ Query32.772
NC_008150:2451872Yersinia pestis Antiqua, complete genome75.4412 %Subject ←→ Query32.8575
NC_008150:844727Yersinia pestis Antiqua, complete genome75.3339 %Subject ←→ Query33.1448
NC_011750:1978801Escherichia coli IAI39 chromosome, complete genome75.386 %Subject ←→ Query33.1799
NC_005810:2905362Yersinia pestis biovar Microtus str. 91001, complete genome75.4657 %Subject ←→ Query33.2442
NC_006155:3212796Yersinia pseudotuberculosis IP 32953, complete genome75.2145 %Subject ←→ Query33.6056
NC_008149:2802392Yersinia pestis Nepal516, complete genome75.9222 %Subject ←→ Query33.694
NC_010465:62348*Yersinia pseudotuberculosis YPIII, complete genome75.0582 %Subject ←→ Query34.1617
NC_010465:3431500*Yersinia pseudotuberculosis YPIII, complete genome75.867 %Subject ←→ Query34.3332
NC_003143:1233128Yersinia pestis CO92, complete genome75.6464 %Subject ←→ Query34.411
CP002185:3627992*Escherichia coli W, complete genome75.2604 %Subject ←→ Query35.0316
NC_012912:1053618Dickeya zeae Ech1591, complete genome75.4749 %Subject ←→ Query35.8787
NC_014228:1336466*Xenorhabdus nematophila ATCC 19061, complete genome75.095 %Subject ←→ Query36.126
NC_014228:3534378Xenorhabdus nematophila ATCC 19061, complete genome76.6146 %Subject ←→ Query37.5253
NC_012962:3463644Photorhabdus asymbiotica, complete genome75.674 %Subject ←→ Query39.6218
NC_013592:2059138Dickeya dadantii Ech586, complete genome75.3309 %Subject ←→ Query41.1373
NC_005126:1613818Photorhabdus luminescens subsp. laumondii TTO1, complete genome76.5993 %Subject ←→ Query42.1275
NC_013592:956829*Dickeya dadantii Ech586, complete genome75.3554 %Subject ←→ Query47.1245
NC_013956:595320*Pantoea ananatis LMG 20103 chromosome, complete genome75.3523 %Subject ←→ Query47.147