Pre_GI: OUP Neighbours

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Query: NC_003143:2137945 Yersinia pestis CO92, complete genome

D: 37.3318

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a recent Orientalis subtype isolated in the USA from a patient who died of pneumonic plague after acquiring the disease from an infected cat. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Number of Neighbours: 109

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_008150:1420825*Yersinia pestis Antiqua, complete genome97.1078 %Subject ←→ Query37.0184
NC_005810:1794490*Yersinia pestis biovar Microtus str. 91001, complete genome96.8934 %Subject ←→ Query37.035
NC_012779:3016327Edwardsiella ictaluri 93-146, complete genome82.1538 %Subject ←→ Query37.6194
NC_012912:647369Dickeya zeae Ech1591, complete genome81.5931 %Subject ←→ Query37.7391
NC_014500:1646854*Dickeya dadantii 3937 chromosome, complete genome81.2684 %Subject ←→ Query37.9513
NC_012880:2480000Dickeya dadantii Ech703, complete genome81.1183 %Subject ←→ Query30.1678
NC_014500:3175283Dickeya dadantii 3937 chromosome, complete genome80.9835 %Subject ←→ Query44.4588
NC_015663:1902344*Enterobacter aerogenes KCTC 2190 chromosome, complete genome80.867 %Subject ←→ Query31.1284
NC_012880:2778795Dickeya dadantii Ech703, complete genome80.4994 %Subject ←→ Query36.5333
NC_014500:2934232*Dickeya dadantii 3937 chromosome, complete genome80.3064 %Subject ←→ Query37.5286
NC_012880:913698Dickeya dadantii Ech703, complete genome80.3002 %Subject ←→ Query30.49
NC_006905:3942753Salmonella enterica subsp. enterica serovar Choleraesuis str80.2482 %Subject ←→ Query35.749
NC_010694:2189652*Erwinia tasmaniensis, complete genome80.2267 %Subject ←→ Query37.4179
NC_013716:1756545*Citrobacter rodentium ICC168, complete genome80.0797 %Subject ←→ Query33.4286
NC_012912:777592*Dickeya zeae Ech1591, complete genome79.9418 %Subject ←→ Query33.9737
NC_009648:3720000*Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome79.9112 %Subject ←→ Query36.7036
NC_012779:1629731Edwardsiella ictaluri 93-146, complete genome79.8376 %Subject ←→ Query35.0944
NC_013508:876431*Edwardsiella tarda EIB202, complete genome79.8223 %Subject ←→ Query41.7282
NC_003198:3824187Salmonella enterica subsp. enterica serovar Typhi str. CT18,79.7733 %Subject ←→ Query35.4207
NC_004631:3809678Salmonella enterica subsp. enterica serovar Typhi Ty2, complete79.7488 %Subject ←→ Query36.1376
NC_014500:894136Dickeya dadantii 3937 chromosome, complete genome79.6569 %Subject ←→ Query37.8586
NC_013282:3216226*Cronobacter turicensis, complete genome79.3444 %Subject ←→ Query41.2788
NC_010694:614985Erwinia tasmaniensis, complete genome79.3168 %Subject ←→ Query35.5876
NC_009778:3454790Enterobacter sakazakii ATCC BAA-894, complete genome79.2065 %Subject ←→ Query36.7583
NC_015968:2195645Enterobacter asburiae LF7a chromosome, complete genome78.9124 %Subject ←→ Query33.0849
NC_011080:3976441Salmonella enterica subsp. enterica serovar Newport str. SL254,78.8113 %Subject ←→ Query36.5166
NC_011149:3930358Salmonella enterica subsp. enterica serovar Agona str. SL483,78.7929 %Subject ←→ Query38.0507
NC_011083:4020000Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,78.7898 %Subject ←→ Query37.6885
NC_012779:957558Edwardsiella ictaluri 93-146, complete genome78.7163 %Subject ←→ Query38.2879
NC_012779:3176820*Edwardsiella ictaluri 93-146, complete genome78.5907 %Subject ←→ Query39.7546
NC_003197:4005857Salmonella typhimurium LT2, complete genome78.5846 %Subject ←→ Query36.3904
NC_015968:4389871Enterobacter asburiae LF7a chromosome, complete genome78.5754 %Subject ←→ Query30.7332
NC_012779:1820244*Edwardsiella ictaluri 93-146, complete genome78.511 %Subject ←→ Query33.3621
NC_012779:2424967*Edwardsiella ictaluri 93-146, complete genome78.5049 %Subject ←→ Query35.992
NC_013282:3719500*Cronobacter turicensis, complete genome78.4835 %Subject ←→ Query31.6817
NC_012779:261438*Edwardsiella ictaluri 93-146, complete genome78.3333 %Subject ←→ Query37.9045
NC_006511:3794017Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC78.174 %Subject ←→ Query37.3602
NC_012912:1229333Dickeya zeae Ech1591, complete genome78.1495 %Subject ←→ Query32.2592
NC_010102:2881714Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,78.1066 %Subject ←→ Query32.0373
NC_010067:632683Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete78.03 %Subject ←→ Query35.8098
NC_014562:1883517*Pantoea vagans C9-1 chromosome, complete genome77.9197 %Subject ←→ Query34.2182
NC_013508:275081*Edwardsiella tarda EIB202, complete genome77.9075 %Subject ←→ Query39.2554
NC_006905:2805877*Salmonella enterica subsp. enterica serovar Choleraesuis str77.8493 %Subject ←→ Query39.786
NC_009648:293052*Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome77.8217 %Subject ←→ Query43.5401
NC_014562:1935088Pantoea vagans C9-1 chromosome, complete genome77.8002 %Subject ←→ Query30.3988
NC_010102:3955479Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,77.7665 %Subject ←→ Query37.2943
NC_012779:2664849Edwardsiella ictaluri 93-146, complete genome77.7482 %Subject ←→ Query33.7832
NC_013283:113660Cronobacter turicensis plasmid pCTU1, complete sequence77.7482 %Subject ←→ Query42.151
NC_012779:2928000*Edwardsiella ictaluri 93-146, complete genome77.7145 %Subject ←→ Query41.5453
NC_003198:2703013*Salmonella enterica subsp. enterica serovar Typhi str. CT18,77.7053 %Subject ←→ Query38.1505
NC_014561:153143Pantoea vagans C9-1 plasmid pPag1, complete sequence77.6777 %Subject ←→ Query28.1767
NC_012912:1295653Dickeya zeae Ech1591, complete genome77.6256 %Subject ←→ Query31.554
NC_012779:916000Edwardsiella ictaluri 93-146, complete genome77.6164 %Subject ←→ Query32.2167
NC_006511:682863*Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC77.5858 %Subject ←→ Query36.3874
NC_013508:1262333Edwardsiella tarda EIB202, complete genome77.4632 %Subject ←→ Query32.8692
NC_003143:4006884Yersinia pestis CO92, complete genome77.3897 %Subject ←→ Query29.6176
NC_013282:1256769Cronobacter turicensis, complete genome77.3836 %Subject ←→ Query38.8742
NC_004631:685357*Salmonella enterica subsp. enterica serovar Typhi Ty2, complete77.3407 %Subject ←→ Query36.1113
NC_015968:204969*Enterobacter asburiae LF7a chromosome, complete genome77.3192 %Subject ←→ Query30.2205
NC_011149:2294500Salmonella enterica subsp. enterica serovar Agona str. SL483,77.2763 %Subject ←→ Query38.0253
NC_012779:2586175Edwardsiella ictaluri 93-146, complete genome77.2733 %Subject ←→ Query45.323
NC_006155:4302826Yersinia pseudotuberculosis IP 32953, complete genome77.2549 %Subject ←→ Query30.1556
NC_012917:4328463Pectobacterium carotovorum subsp. carotovorum PC1, complete genome77.2059 %Subject ←→ Query31.405
NC_011080:2342672Salmonella enterica subsp. enterica serovar Newport str. SL254,77.1906 %Subject ←→ Query37.4165
NC_011080:2789744*Salmonella enterica subsp. enterica serovar Newport str. SL254,77.1844 %Subject ←→ Query36.512
NC_015663:770485*Enterobacter aerogenes KCTC 2190 chromosome, complete genome77.163 %Subject ←→ Query39.8332
NC_004547:667988*Erwinia carotovora subsp. atroseptica SCRI1043, complete genome77.1569 %Subject ←→ Query39.9614
NC_003198:2297837Salmonella enterica subsp. enterica serovar Typhi str. CT18,77.0803 %Subject ←→ Query37.159
NC_012912:2800884*Dickeya zeae Ech1591, complete genome77.0803 %Subject ←→ Query31.095
NC_010634:4234932Yersinia pseudotuberculosis PB1/+, complete genome77.0772 %Subject ←→ Query30.3016
NC_013956:4579759Pantoea ananatis LMG 20103 chromosome, complete genome77.0619 %Subject ←→ Query34.8158
NC_012912:2285778Dickeya zeae Ech1591, complete genome77.0466 %Subject ←→ Query33.4887
NC_012917:4646491Pectobacterium carotovorum subsp. carotovorum PC1, complete genome77.0312 %Subject ←→ Query32.6958
NC_006905:2355290Salmonella enterica subsp. enterica serovar Choleraesuis str77.0006 %Subject ←→ Query37.6094
NC_013508:2130681*Edwardsiella tarda EIB202, complete genome76.9822 %Subject ←→ Query42.2435
NC_013508:1862896Edwardsiella tarda EIB202, complete genome76.9516 %Subject ←→ Query33.0734
NC_015566:4205854*Serratia sp. AS12 chromosome, complete genome76.8781 %Subject ←→ Query30.8457
NC_013508:63914Edwardsiella tarda EIB202, complete genome76.875 %Subject ←→ Query32.531
NC_004631:283289*Salmonella enterica subsp. enterica serovar Typhi Ty2, complete76.8352 %Subject ←→ Query31.6756
NC_009832:1946401Serratia proteamaculans 568, complete genome76.7892 %Subject ←→ Query35.908
NC_012779:3316877Edwardsiella ictaluri 93-146, complete genome76.7739 %Subject ←→ Query34.9445
NC_004631:2755306Salmonella enterica subsp. enterica serovar Typhi Ty2, complete76.7678 %Subject ←→ Query30.7575
NC_003198:2769449Salmonella enterica subsp. enterica serovar Typhi str. CT18,76.7678 %Subject ←→ Query31.0494
NC_013282:646569Cronobacter turicensis, complete genome76.7126 %Subject ←→ Query30.8062
NC_012779:996879Edwardsiella ictaluri 93-146, complete genome76.5839 %Subject ←→ Query39.7678
NC_010102:283364*Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,76.5043 %Subject ←→ Query33.8947
NC_012779:2064582Edwardsiella ictaluri 93-146, complete genome76.4767 %Subject ←→ Query37.0151
NC_012779:3570720*Edwardsiella ictaluri 93-146, complete genome76.4553 %Subject ←→ Query34.4297
NC_009778:1902995Enterobacter sakazakii ATCC BAA-894, complete genome76.3664 %Subject ←→ Query35.1593
NC_012779:610509*Edwardsiella ictaluri 93-146, complete genome76.3419 %Subject ←→ Query37.2815
NC_013716:4824541*Citrobacter rodentium ICC168, complete genome76.3235 %Subject ←→ Query38.2235
NC_014305:126029Erwinia billingiae Eb661 plasmid pEB170, complete sequence76.25 %Subject ←→ Query35.5879
NC_012779:2755338*Edwardsiella ictaluri 93-146, complete genome76.2439 %Subject ←→ Query31.2622
NC_012779:3652737Edwardsiella ictaluri 93-146, complete genome76.1703 %Subject ←→ Query33.7001
NC_012779:2281700*Edwardsiella ictaluri 93-146, complete genome76.155 %Subject ←→ Query40.1776
NC_014500:2616423Dickeya dadantii 3937 chromosome, complete genome75.8027 %Subject ←→ Query29.9702
NC_006511:3364448*Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC75.7721 %Subject ←→ Query38.4606
NC_005773:4539751*Pseudomonas syringae pv. phaseolicola 1448A, complete genome75.7445 %Subject ←→ Query34.6607
NC_012779:1449500*Edwardsiella ictaluri 93-146, complete genome75.6985 %Subject ←→ Query41.6091
NC_010694:962383Erwinia tasmaniensis, complete genome75.5729 %Subject ←→ Query30.0928
NC_009792:808332Citrobacter koseri ATCC BAA-895, complete genome75.5453 %Subject ←→ Query35.0274
NC_011149:2040396Salmonella enterica subsp. enterica serovar Agona str. SL483,75.3248 %Subject ←→ Query37.9381
NC_012912:4737703Dickeya zeae Ech1591, complete genome75.2053 %Subject ←→ Query29.5142
NC_012779:305969Edwardsiella ictaluri 93-146, complete genome75.2022 %Subject ←→ Query39.836
NC_014562:1698253Pantoea vagans C9-1 chromosome, complete genome75.1777 %Subject ←→ Query33.9839
NC_014304:77715Erwinia billingiae Eb661 plasmid pEB102, complete sequence75.1716 %Subject ←→ Query34.3324
NC_007645:2533274Hahella chejuensis KCTC 2396, complete genome75.1011 %Subject ←→ Query34.5787
NC_004578:2671508Pseudomonas syringae pv. tomato str. DC3000, complete genome75.0123 %Subject ←→ Query34.0893
NC_008563:3119284Escherichia coli APEC O1, complete genome75.0123 %Subject ←→ Query31.9127