Pre_GI: OUP Neighbours

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Query: NC_003112:1594000 Neisseria meningitidis MC58, complete genome

D: 32.6666

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Number of Neighbours: 16

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_002946:684728Neisseria gonorrhoeae FA 1090, complete genome76.1734 %Subject ←→ Query30.2475
NC_003116:1734000Neisseria meningitidis Z2491, complete genome78.0024 %Subject ←→ Query30.3786
NC_010120:1313500Neisseria meningitidis 053442, complete genome75.4596 %Subject ←→ Query31.5054
NC_003116:658879Neisseria meningitidis Z2491, complete genome75.239 %Subject ←→ Query31.8631
NC_014752:1391615Neisseria lactamica ST-640, complete genome75.6036 %Subject ←→ Query32.3222
NC_010120:144000*Neisseria meningitidis 053442, complete genome84.8131 %Subject ←→ Query32.4921
NC_010120:609323*Neisseria meningitidis 053442, complete genome78.5172 %Subject ←→ Query33.1254
NC_008767:1739344Neisseria meningitidis FAM18, complete genome78.0974 %Subject ←→ Query33.4813
NC_008767:613394*Neisseria meningitidis FAM18, complete genome78.0944 %Subject ←→ Query34.1821
NC_008767:1829500*Neisseria meningitidis FAM18, complete genome77.6103 %Subject ←→ Query34.2169
NC_008767:1321129*Neisseria meningitidis FAM18, complete genome76.2714 %Subject ←→ Query34.4104
NC_014752:1063506Neisseria lactamica ST-640, complete genome77.5031 %Subject ←→ Query35.8436
NC_003116:291661*Neisseria meningitidis Z2491, complete genome76.011 %Subject ←→ Query39.4107
NC_014752:197000*Neisseria lactamica ST-640, complete genome75.1103 %Subject ←→ Query40.1397
NC_003112:2215184*Neisseria meningitidis MC58, complete genome77.0374 %Subject ←→ Query40.7794
NC_010120:1065833Neisseria meningitidis 053442, complete genome76.3051 %Subject ←→ Query41.3655