Pre_GI: OUP Neighbours

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Query: NC_002950:1981155 Porphyromonas gingivalis W83, complete genome

D: 32.6605

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain (also known as HG66) is virulent in a mouse model and has been extensively studied. It was originally isolated by H. Werner in the 1950s in Bonn, Germany, from an unknown human infection. Associated with severe and chronic periodontal disease. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin.Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

Number of Neighbours: 12

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_015571:168617*Porphyromonas gingivalis TDC60, complete genome83.4957 %Subject ←→ Query35.8726
NC_015571:722815*Porphyromonas gingivalis TDC60, complete genome81.6422 %Subject ←→ Query31.2952
NC_010729:1344903*Porphyromonas gingivalis ATCC 33277, complete genome79.9908 %Subject ←→ Query28.6722
NC_010729:1385217Porphyromonas gingivalis ATCC 33277, complete genome78.4007 %Subject ←→ Query26.4044
NC_015571:1265121*Porphyromonas gingivalis TDC60, complete genome77.9228 %Subject ←→ Query37.7493
NC_002950:2098454Porphyromonas gingivalis W83, complete genome76.6789 %Subject ←→ Query29.9884
NC_002950:1270132Porphyromonas gingivalis W83, complete genome76.5411 %Subject ←→ Query34.3389
NC_015571:290355*Porphyromonas gingivalis TDC60, complete genome76.1979 %Subject ←→ Query32.3231
NC_015571:1207000Porphyromonas gingivalis TDC60, complete genome75.7384 %Subject ←→ Query33.9518
NC_010729:1462135Porphyromonas gingivalis ATCC 33277, complete genome75.5484 %Subject ←→ Query29.2315
NC_015571:1030527Porphyromonas gingivalis TDC60, complete genome75.1256 %Subject ←→ Query34.085
NC_010729:2147268*Porphyromonas gingivalis ATCC 33277, complete genome75.0858 %Subject ←→ Query31.9808