Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_017514: Neisseria meningitidis M01-240149 chromosome, complete genome

NCBI: NC_017514

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
196911*12240325493Island text2.3267838.731839.5562Neighbours24BLASTN+96911.gbk
244661649709950484Island text2.2592438.649522.6585Neighbours24BLASTN+446616.gbk
376100078122620227Island text1.9145136.693249.9975Neighbours24BLASTN+761000.gbk
486348588947325989Island text1.6781432.841730.1562Neighbours24BLASTN+863485.gbk
51396000141924523246Island text1.6116732.918348.9438Neighbours24BLASTN1396000.gbk
61491235*150923017996Island text1.53832.147831.7741Neighbours24BLASTN1491235.gbk
71520245*154123320989Island text2.7068538.438222.6711Neighbours35BLASTN+1520245.gbk
81568591*159581827228Island text1.4455832.295740.4373Neighbours35BLASTN+1568591.gbk
91640355*166659926245Island text1.5385430.514331.4655Neighbours24BLASTN+1640355.gbk
101721416175674235327Island text1.6284331.53450.1482Neighbours24BLASTN+1721416.gbk
111885154190359918446Island text2.4182535.578534.4554Neighbours24BLASTN+1885154.gbk
122096452*212725930808Island text2.8674639.459924.4555Neighbours320BLASTN+2096452.gbk
132165166*219968434519Island text1.8696635.122836.5921Neighbours24BLASTN+2165166.gbk