Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_017246: Brucella melitensis M5-90 chromosome chromosome I, complete

NCBI: NC_017246

Host Lineage: Brucella melitensis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
126491728809923183Island text1.6052829.588727.8901Neighbours11BLASTN264917.gbk
252882555559926775Island text2.0247929.779330.7689Neighbours41BLASTN+528825.gbk
372714374564418502Island text1.50928.678320.7273Neighbours11BLASTN+727143.gbk
4956868*98233625469Island text1.7015732.313127.9171Neighbours11BLASTN+956868.gbk
51942293*196659924307Island text1.8272230.758143.0217Neighbours46BLASTN+1942293.gbk