Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_014039: Propionibacterium acnes SK137 chromosome, complete genome

NCBI: NC_014039

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
1152364170426469Island text1.6300427.230732.9148Neighbours11BLASTN+15236.gbk
215163117450422874Island text1.627120.899241.5215Neighbours11BLASTN+IslandViewer 151631.gbk
326112628731726192Island text1.7561325.289846.0303Neighbours11BLASTN+261126.gbk
4334892*35832823437Island text1.7346924.347242.8389Neighbours11BLASTN334892.gbk
5499233*52279623564Island text1.494324.46544.0005Neighbours11BLASTN499233.gbk
670842772779219366Island text1.6093223.072743.4584Neighbours11BLASTN708427.gbk
7869826*90861838793Island text1.9240328.25846.6704Neighbours11BLASTN+869826.gbk
81238500126344824949Island text1.8104424.894641.7029Neighbours11BLASTN1238500.gbk
91766049*178641920371Island text1.4975222.580331.4959Neighbours11BLASTN+1766049.gbk
101813205183638923185Island text1.6562124.657743.1315Neighbours11BLASTN+1813205.gbk
112320307*234626325957Island text1.8772228.308847.6317Neighbours11BLASTN+2320307.gbk
122386347240678020434Island text1.5487125.45640.536Neighbours11BLASTN+2386347.gbk
132479500*250599926500Island text1.66126.234746.1185Neighbours11BLASTN2479500.gbk