Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_012207: Mycobacterium bovis BCG str. Tokyo 172, complete genome

NCBI: NC_012207

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
147750050076723268Island text1.8359719.255628.4992Neighbours11BLASTN+477500.gbk
283103085360922580Island text1.7316817.586317.3942Neighbours11BLASTN+831030.gbk
31097228*111789920672Island text1.539118.061824.5389Neighbours11BLASTN+IslandViewer 1097228.gbk
41681971170520423234Island text1.7290620.372625.2379Neighbours11BLASTN+1681971.gbk
51848091186924521155Island text1.6896115.843927.9998Neighbours11BLASTN1848091.gbk
62573562*259732923768Island text1.4030819.218118.4249Neighbours11BLASTN+2573562.gbk
72747599277148023882Island text1.4894516.883521.1719Neighbours11BLASTN2747599.gbk
83063039308477921741Island text1.5472721.275734.5231Neighbours11BLASTN+IslandViewer 3063039.gbk
93237440325728519846Island text1.5136216.566430.2491Neighbours11BLASTNIslandViewer 3237440.gbk
103421144344072619583Island text1.5666715.804419.8197Neighbours11BLASTN+IslandViewer 3421144.gbk
113766978379261425637Island text1.4094919.315428.6332Neighbours11BLASTN+IslandViewer 3766978.gbk