Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_008710: Borrelia turicatae 91E135, complete genome

NCBI: NC_008710

Host Lineage: Borrelia turicatae; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
179100*10268323584Island text1.8094817.476335.1931Neighbours21BLASTN79100.gbk
2108057*13056722511Island text2.2216718.432934.0553Neighbours21BLASTN108057.gbk
327720731812040914Island text1.83317.756234.7651Neighbours21BLASTN277207.gbk
4386376*40547419099Island text1.7514717.75933.4511Neighbours21BLASTN+386376.gbk
5488815*50960620792Island text2.5068817.391335.7248Neighbours21BLASTN+488815.gbk
6577696*60295325258Island text1.6738116.853130.1377Neighbours21BLASTN+577696.gbk
7621822*66159939778Island text2.4360616.333332.0538Neighbours21BLASTNIslandViewer 621822.gbk
8703740*75456050821Island text1.8823317.949935.4423Neighbours21BLASTN+703740.gbk
9819389*84556126173Island text1.9140316.983837.4223Neighbours21BLASTN+IslandViewer 819389.gbk
10900586*92799927414Island text2.6483916.989936.5513Neighbours21BLASTN+900586.gbk