Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_007797: Anaplasma phagocytophilum HZ, complete genome

NCBI: NC_007797

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
1107950*13067222723Island text3.0686228.465553.8129Neighbours21BLASTN107950.gbk
2411630*43160119972Island text2.3918931.147953.5985Neighbours21BLASTN+411630.gbk
3441782*46051218731Island text2.2637529.088651.6872Neighbours21BLASTN441782.gbk
469294471309920156Island text2.3144930.626452.7582Neighbours21+692944.gbk
5914500*93405419555Island text1.808331.099247.8088Neighbours314BLASTN+914500.gbk
61016456*103559919144Island text1.5679131.040254.9123Neighbours314BLASTN+1016456.gbk
71451804*147799926196Island text2.0707529.778749.8721Neighbours21BLASTN+1451804.gbk