n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)
n0_4mer:D = Distance between local and global OU patterns
n0_4mer:PS = Distance between 2 strands of same DNA molecule
Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS
NC_006833: Wolbachia endosymbiont strain TRS of Brugia malayi, complete
NCBI: NC_006833
Host Lineage: Wolbachia endosymbiont of Brugia malayi; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: A nematode endosymbiont. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission. This strain naturally infects Brugia malayi, a parasitic filarial nematode that causes lymphatic filariasis, one of the most devastating diseases in humans. The endosymbiont plays important roles in the biology of the nematide host. One of the known such effects are aberrant sex ratios in the host, parthenogenesis and feminization of genetic males, etc.