Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_006085: Propionibacterium acnes KPA171202, complete genome

NCBI: NC_006085

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
1152464566630421Island text1.6140126.663134.0985Neighbours11BLASTN+15246.gbk
223412725583521709Island text1.9466527.590848.8801Neighbours11BLASTN234127.gbk
330856732922620660Island text1.8004423.32545.3039Neighbours11BLASTN308567.gbk
4481231*50479923569Island text1.49924.282643.6046Neighbours11BLASTN481231.gbk
5854500*88927234773Island text1.9374428.234146.3831Neighbours11BLASTN+IslandViewer 854500.gbk
692560495910233499Island text2.4079728.704935.4507Neighbours11BLASTN+IslandViewer 925604.gbk
71234587126026325677Island text2.0077728.033846.5835Neighbours11BLASTN1234587.gbk
81379370*140289723528Island text2.7112532.551741.2732BLASTN+IslandViewer 1379370.gbk
91859191188064221452Island text1.6838524.951442.295Neighbours11BLASTN+1859191.gbk
102384892*241156026669Island text1.8629727.407946.6475Neighbours11BLASTN+2384892.gbk
112544421*257099926579Island text1.7087825.816245.8017Neighbours11BLASTN2544421.gbk