Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_003317: Brucella melitensis 16M chromosome I, complete sequence

NCBI: NC_003317

Host Lineage: Brucella melitensis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain was isolated from an infected goat and is pathogenic in humans. Causes brucellosis and undulant fever. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
148375*7459926225Island text2.0831139.032132.7685Neighbours11BLASTN+IslandViewer 48375.gbk
2190975*21627025296Island text1.781431.891842.9867Neighbours11BLASTN+190975.gbk
3392271*41315320883Island text1.7906330.74143.4184Neighbours11BLASTN+392271.gbk
41030220*105366423445Island text1.7723333.500729.5054Neighbours11BLASTN+IslandViewer 1030220.gbk
51263562*128225718696Island text1.4878431.085824.0864Neighbours11BLASTN+IslandViewer 1263562.gbk
61443874146565121778Island text1.5034927.477229.2759Neighbours11BLASTN+IslandViewer 1443874.gbk
71719546*174739327848Island text1.7113729.895232.7978Neighbours11BLASTN+IslandViewer 1719546.gbk